Differential effect of prostaglandins E1 and E2 on lipopolysaccharide-induced adhesion molecule expression on human monocytes

The effect of prostaglandins E1 and E2 on the 1 ng/ml lipopolysaccharide-induced expression of intercellular adhesion molecule (ICAM)-1, B7.1, B7.2, CD40 and CD40 ligand (CD40L) on monocytes was examined. Prostaglandin E1 suppressed B7.1 and CD40 expression, but prostaglandin E2 did not effect on an...

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Veröffentlicht in:	European journal of pharmacology 2005-04, Vol.512 (2-3), p.223-230
Hauptverfasser:	TAKAHASHI, Hideo K, IWAGAKI, Hiromi, TAMURA, Ryuji, KATSUNO, Goutaro, DONG XUE, SUGITA, Sachi, MORI, Shuji, YOSHINO, Tadashi, TANAKA, Noriaki, NISHIBORI, Masahiro
Format:	Artikel
Sprache:	eng
Schlagworte:	Alprostadil - analogs & derivatives Alprostadil - pharmacology Antibodies, Monoclonal - pharmacology Antigens, CD - immunology Antigens, CD - metabolism B7-1 Antigen - immunology B7-1 Antigen - metabolism B7-2 Antigen Biological and medical sciences CD40 Antigens - immunology CD40 Antigens - metabolism CD40 Ligand - immunology CD40 Ligand - metabolism Cell Adhesion Molecules - metabolism Cell Proliferation - drug effects Dinoprostone - analogs & derivatives Dinoprostone - pharmacology Dose-Response Relationship, Drug Enzyme-Linked Immunosorbent Assay Flow Cytometry Humans Intercellular Adhesion Molecule-1 - immunology Intercellular Adhesion Molecule-1 - metabolism Lipopolysaccharides - pharmacology Medical sciences Membrane Glycoproteins - immunology Membrane Glycoproteins - metabolism Methyl Ethers - pharmacology Monocytes - cytology Monocytes - drug effects Monocytes - metabolism Pharmacology. Drug treatments Pyridines - pharmacology T-Lymphocytes - cytology T-Lymphocytes - drug effects Tumor Necrosis Factor-alpha - metabolism
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