Ultra sensitive trace gas detection for biomedical applications

We present an overview of our recent progress on spectroscopic trace gas detection for biomedical applications. The latest developments of cavity-enhanced spectroscopy as well as magnetic rotation spectroscopy lead to unprecedented sensitivity and specificity. The current detection limits of our las...

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Veröffentlicht in:Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy Molecular and biomolecular spectroscopy, 2006-04, Vol.63 (5), p.963-969
Hauptverfasser: Mürtz, Manfred, Halmer, Daniel, Horstjann, Markus, Thelen, Sven, Hering, Peter
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container_issue 5
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container_title Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy
container_volume 63
creator Mürtz, Manfred
Halmer, Daniel
Horstjann, Markus
Thelen, Sven
Hering, Peter
description We present an overview of our recent progress on spectroscopic trace gas detection for biomedical applications. The latest developments of cavity-enhanced spectroscopy as well as magnetic rotation spectroscopy lead to unprecedented sensitivity and specificity. The current detection limits of our laser spectroscopic approaches are in the picomolar to nanomolar range, depending on the molecular compound. The time resolution of the measurements is down to the sub-second range. This very high sensitivity and time resolution open up exciting perspectives for novel analytical tasks in biomedical research and clinical diagnosis.
doi_str_mv 10.1016/j.saa.2005.11.015
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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Biomedical Research
Difference frequency generation
Fiber Optic Technology
Free Radicals - metabolism
Gases - analysis
Humans
Infrared spectroscopy
Lasers
Nitric Oxide - metabolism
Quantum cascade laser
Sensitivity and Specificity
Trace gas
title Ultra sensitive trace gas detection for biomedical applications
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