Upregulation of transferrin receptor 2 and ferroportin 1 mRNA in the liver of patients with chronic hepatitis C

Background: Iron accumulation has been reported to be associated with progression of liver injury. The mechanism of iron accumulation in the liver is not known. In the present study, hepatic messenger RNA (mRNA) expression of transferrin receptor (TfR)1, TfR2, and ferroportin (FP)1 was measured in...

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Veröffentlicht in:	Journal of gastroenterology and hepatology 2005-04, Vol.20 (4), p.562-569
Hauptverfasser:	TAKEO, MASAKI, KOBAYASHI, YOSHINAO, FUJITA, NAOKI, URAWA, NAOHITO, IWASA, MOTOH, HORIIKE, SHINICHIRO, TANAKA, HIDEAKI, KAITO, MASAHIKO, ADACHI, YUKIHIKO
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Cation Transport Proteins - metabolism Coloring Agents Female Ferrocyanides hepatitis C virus Hepatitis C, Chronic - metabolism Human viral diseases Humans Infectious diseases iron Liver - metabolism Male Medical sciences Middle Aged Polymerase Chain Reaction Receptors, Transferrin - metabolism RNA, Messenger - metabolism Statistics, Nonparametric total hepatic iron score Up-Regulation Viral diseases Viral diseases of the digestive system Viral hepatitis
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