Transfusion of 7-day-old amotosalen photochemically treated buffy-coat platelets to patients with thrombocytopenia: a pilot study

BACKGROUND: Photochemical treatment (PCT) of platelets (PLTs) with amotosalen and ultraviolet A light to inactivate bacteria may facilitate extension of storage from 5 to 7 days. STUDY DESIGN AND METHODS: A randomized, double‐blinded, crossover, noninferiority, single‐site pilot study utilizing po...

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Veröffentlicht in:	Transfusion (Philadelphia, Pa.) Pa.), 2006-03, Vol.46 (3), p.424-433
Hauptverfasser:	Simonsen, Anne C., Johansson, Pär I., Conlan, Maureen G., Jacquet, Michele, Lin, Jin-Sying, Junge, Klaus, Lin, Lily, Sørensen, Henning, Borregaard, Niels, Flament, Jocelyne
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy Biological and medical sciences Blood coagulation. Blood cells Blood Preservation Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis Emergency and intensive cardiocirculatory care. Cardiogenic shock. Coronary intensive care Female Fundamental and applied biological sciences. Psychology Furocoumarins - pharmacology Hemostasis - drug effects Humans Intensive care medicine Male Medical sciences Microbial Viability - radiation effects Molecular and cellular biology Pilot Projects Platelet Platelet Transfusion - methods PUVA Therapy - methods Thrombocytopenia - therapy Time Factors Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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