A Lipid-modified Phosphoinositide-specific Phospholipase C (TcPI-PLC) Is Involved in Differentiation of Trypomastigotes to Amastigotes of Trypanosoma cruzi

The phosphoinositide-specific phospholipase C (PI-PLC) is an important component of the inositol phosphate/diacylglycerol signaling pathway. A newly discovered Trypanosoma cruzi PI-PLC (TcPI-PLC) is lipid modified in its N terminus, targeted to its plasma membrane, and believed to play a role in dif...

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Veröffentlicht in:	The Journal of biological chemistry 2005-04, Vol.280 (16), p.16235-16243
Hauptverfasser:	Okura, Michael, Fang, Jianmin, Salto, Maria Laura, Singer, Randall S., Docampo, Roberto, Moreno, Silvia N.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Membrane - metabolism Linear Models Membrane Glycoproteins - metabolism Oligonucleotides, Antisense - metabolism Phosphatidylinositol Diacylglycerol-Lyase - genetics Phosphatidylinositol Diacylglycerol-Lyase - metabolism Phosphoinositide Phospholipase C Protozoan Proteins - metabolism Trypanosoma cruzi Trypanosoma cruzi - cytology Trypanosoma cruzi - enzymology Trypanosoma cruzi - genetics Trypanosoma cruzi - growth & development
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