SRC-3/AIB1- transcriptional coactivator in oncogenesis
Steroid receptor coactivator-3 （SRC-3, also known as NCoA3, AIB 1, p/CIP, RAC3, ACTR, and TRAM 1）, localized on a frequently amplified region, 20q12, has been associated with multiple cancers, including breast, gastric and prostate cancers. Although SRC-3 has been implicated as an oncogene, compelli...
Gespeichert in:
| Veröffentlicht in: | Acta pharmacologica Sinica 2006-04, Vol.27 (4), p.387-394 |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 394 |
|---|---|
| container_issue | 4 |
| container_start_page | 387 |
| container_title | Acta pharmacologica Sinica |
| container_volume | 27 |
| creator | Yan, Jun Tsai, Sophia Y Tsai, Ming-jer |
| description | Steroid receptor coactivator-3 （SRC-3, also known as NCoA3, AIB 1, p/CIP, RAC3, ACTR, and TRAM 1）, localized on a frequently amplified region, 20q12, has been associated with multiple cancers, including breast, gastric and prostate cancers. Although SRC-3 has been implicated as an oncogene, compelling evidence has only recently emerged implicating it as a causal factor in the genesis of human cancers. Here, we summarize recent evidence that indicates aberrant SRC-3 expression is important in hormone-sensitive and -insensitive human cancers. |
| doi_str_mv | 10.1111/j.1745-7254.2006.00315.x |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_67751868</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><cqvip_id>21532959</cqvip_id><sourcerecordid>67751868</sourcerecordid><originalsourceid>FETCH-LOGICAL-c337t-ee6373ce5c96145ef9b0fbbc7fd13fb30e00399ab7a5482380f1f6a25164f8a43</originalsourceid><addsrcrecordid>eNpdkNtOxCAQhonReFh9BW288K4VOgXKpW48JZuYeLgmFGHt2oUVWqNvL3U9JHIDyXwz8_MhlBFckHROFwXhFc15SauixJgVGAOhxfsG2v0tbKY34ySvcA07aC_GRYJKIGIb7RBGQdTAdhG7v5vmcHp2c07yrA_KRR3aVd96p7pMe6X79k31PmSty7zTfm6ciW3cR1tWddEcfN8T9Hh58TC9zme3VzfTs1muAXifG8OAgzZUC0YqaqxosG0aze0TAdsANimTEKrhilZ1CTW2xDJVUsIqW6sKJuhkPXcV_OtgYi-XbdSm65QzfoiScU5JzeoEHv8DF34I6RNRlgQwTQgk6PAbGpqleZKr0C5V-JA_OhIg1kBMJTc34W8KwXJULxdyNCxHw3JUL7_Uy_fUe7TudaofgvkdrlZx5Cj-y6ifvZu_pgWyUfrFtp1JISmUggr4BIZIiQQ</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>213056833</pqid></control><display><type>article</type><title>SRC-3/AIB1- transcriptional coactivator in oncogenesis</title><source>Wiley-Blackwell Journals</source><source>MEDLINE</source><source>Alma/SFX Local Collection</source><source>Free Full-Text Journals in Chemistry</source><creator>Yan, Jun ; Tsai, Sophia Y ; Tsai, Ming-jer</creator><creatorcontrib>Yan, Jun ; Tsai, Sophia Y ; Tsai, Ming-jer</creatorcontrib><description>Steroid receptor coactivator-3 （SRC-3, also known as NCoA3, AIB 1, p/CIP, RAC3, ACTR, and TRAM 1）, localized on a frequently amplified region, 20q12, has been associated with multiple cancers, including breast, gastric and prostate cancers. Although SRC-3 has been implicated as an oncogene, compelling evidence has only recently emerged implicating it as a causal factor in the genesis of human cancers. Here, we summarize recent evidence that indicates aberrant SRC-3 expression is important in hormone-sensitive and -insensitive human cancers.</description><identifier>ISSN: 1671-4083</identifier><identifier>EISSN: 1745-7254</identifier><identifier>DOI: 10.1111/j.1745-7254.2006.00315.x</identifier><identifier>PMID: 16539836</identifier><language>eng</language><publisher>London: Nature Publishing Group UK</publisher><subject>AIB1 ; Animals ; Biomedical and Life Sciences ; Biomedicine ; Breast Neoplasms - metabolism ; Breast Neoplasms - pathology ; Cell Proliferation ; Cell Survival ; Histone Acetyltransferases - chemistry ; Histone Acetyltransferases - genetics ; Histone Acetyltransferases - metabolism ; Humans ; Immunology ; Internal Medicine ; Male ; Medical Microbiology ; Nuclear Receptor Coactivator 3 ; Oncogenes ; Pharmacology/Toxicology ; Prostatic Neoplasms - metabolism ; Prostatic Neoplasms - pathology ; review ; Signal Transduction - physiology ; SRC-3 ; Stomach Neoplasms - metabolism ; Stomach Neoplasms - pathology ; Trans-Activators - chemistry ; Trans-Activators - genetics ; Trans-Activators - metabolism ; Transcription Factors - metabolism ; Vaccine ; 信号转导 ; 共激活剂 ; 肿瘤形成</subject><ispartof>Acta pharmacologica Sinica, 2006-04, Vol.27 (4), p.387-394</ispartof><rights>CPS and SIMM 2006</rights><rights>Copyright Nature Publishing Group Apr 2006</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Uhttp://image.cqvip.com/vip1000/qk/95561A/95561A.jpg</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16539836$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Yan, Jun</creatorcontrib><creatorcontrib>Tsai, Sophia Y</creatorcontrib><creatorcontrib>Tsai, Ming-jer</creatorcontrib><title>SRC-3/AIB1- transcriptional coactivator in oncogenesis</title><title>Acta pharmacologica Sinica</title><addtitle>Acta Pharmacol Sin</addtitle><addtitle>Acta Pharmacologica Sinica</addtitle><description>Steroid receptor coactivator-3 （SRC-3, also known as NCoA3, AIB 1, p/CIP, RAC3, ACTR, and TRAM 1）, localized on a frequently amplified region, 20q12, has been associated with multiple cancers, including breast, gastric and prostate cancers. Although SRC-3 has been implicated as an oncogene, compelling evidence has only recently emerged implicating it as a causal factor in the genesis of human cancers. Here, we summarize recent evidence that indicates aberrant SRC-3 expression is important in hormone-sensitive and -insensitive human cancers.</description><subject>AIB1</subject><subject>Animals</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Breast Neoplasms - metabolism</subject><subject>Breast Neoplasms - pathology</subject><subject>Cell Proliferation</subject><subject>Cell Survival</subject><subject>Histone Acetyltransferases - chemistry</subject><subject>Histone Acetyltransferases - genetics</subject><subject>Histone Acetyltransferases - metabolism</subject><subject>Humans</subject><subject>Immunology</subject><subject>Internal Medicine</subject><subject>Male</subject><subject>Medical Microbiology</subject><subject>Nuclear Receptor Coactivator 3</subject><subject>Oncogenes</subject><subject>Pharmacology/Toxicology</subject><subject>Prostatic Neoplasms - metabolism</subject><subject>Prostatic Neoplasms - pathology</subject><subject>review</subject><subject>Signal Transduction - physiology</subject><subject>SRC-3</subject><subject>Stomach Neoplasms - metabolism</subject><subject>Stomach Neoplasms - pathology</subject><subject>Trans-Activators - chemistry</subject><subject>Trans-Activators - genetics</subject><subject>Trans-Activators - metabolism</subject><subject>Transcription Factors - metabolism</subject><subject>Vaccine</subject><subject>信号转导</subject><subject>共激活剂</subject><subject>肿瘤形成</subject><issn>1671-4083</issn><issn>1745-7254</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><recordid>eNpdkNtOxCAQhonReFh9BW288K4VOgXKpW48JZuYeLgmFGHt2oUVWqNvL3U9JHIDyXwz8_MhlBFckHROFwXhFc15SauixJgVGAOhxfsG2v0tbKY34ySvcA07aC_GRYJKIGIb7RBGQdTAdhG7v5vmcHp2c07yrA_KRR3aVd96p7pMe6X79k31PmSty7zTfm6ciW3cR1tWddEcfN8T9Hh58TC9zme3VzfTs1muAXifG8OAgzZUC0YqaqxosG0aze0TAdsANimTEKrhilZ1CTW2xDJVUsIqW6sKJuhkPXcV_OtgYi-XbdSm65QzfoiScU5JzeoEHv8DF34I6RNRlgQwTQgk6PAbGpqleZKr0C5V-JA_OhIg1kBMJTc34W8KwXJULxdyNCxHw3JUL7_Uy_fUe7TudaofgvkdrlZx5Cj-y6ifvZu_pgWyUfrFtp1JISmUggr4BIZIiQQ</recordid><startdate>20060401</startdate><enddate>20060401</enddate><creator>Yan, Jun</creator><creator>Tsai, Sophia Y</creator><creator>Tsai, Ming-jer</creator><general>Nature Publishing Group UK</general><general>Nature Publishing Group</general><scope>2RA</scope><scope>92L</scope><scope>CQIGP</scope><scope>W91</scope><scope>~WA</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>3V.</scope><scope>7QP</scope><scope>7QR</scope><scope>7T5</scope><scope>7TK</scope><scope>7TO</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8FD</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>H94</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>LK8</scope><scope>M0S</scope><scope>M1P</scope><scope>M7N</scope><scope>M7P</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20060401</creationdate><title>SRC-3/AIB1- transcriptional coactivator in oncogenesis</title><author>Yan, Jun ; Tsai, Sophia Y ; Tsai, Ming-jer</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c337t-ee6373ce5c96145ef9b0fbbc7fd13fb30e00399ab7a5482380f1f6a25164f8a43</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>AIB1</topic><topic>Animals</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Breast Neoplasms - metabolism</topic><topic>Breast Neoplasms - pathology</topic><topic>Cell Proliferation</topic><topic>Cell Survival</topic><topic>Histone Acetyltransferases - chemistry</topic><topic>Histone Acetyltransferases - genetics</topic><topic>Histone Acetyltransferases - metabolism</topic><topic>Humans</topic><topic>Immunology</topic><topic>Internal Medicine</topic><topic>Male</topic><topic>Medical Microbiology</topic><topic>Nuclear Receptor Coactivator 3</topic><topic>Oncogenes</topic><topic>Pharmacology/Toxicology</topic><topic>Prostatic Neoplasms - metabolism</topic><topic>Prostatic Neoplasms - pathology</topic><topic>review</topic><topic>Signal Transduction - physiology</topic><topic>SRC-3</topic><topic>Stomach Neoplasms - metabolism</topic><topic>Stomach Neoplasms - pathology</topic><topic>Trans-Activators - chemistry</topic><topic>Trans-Activators - genetics</topic><topic>Trans-Activators - metabolism</topic><topic>Transcription Factors - metabolism</topic><topic>Vaccine</topic><topic>信号转导</topic><topic>共激活剂</topic><topic>肿瘤形成</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Yan, Jun</creatorcontrib><creatorcontrib>Tsai, Sophia Y</creatorcontrib><creatorcontrib>Tsai, Ming-jer</creatorcontrib><collection>维普_期刊</collection><collection>中文科技期刊数据库-CALIS站点</collection><collection>维普中文期刊数据库</collection><collection>中文科技期刊数据库-医药卫生</collection><collection>中文科技期刊数据库- 镜像站点</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>ProQuest Central (Corporate)</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Chemoreception Abstracts</collection><collection>Immunology Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Virology and AIDS Abstracts</collection><collection>ProQuest Health and Medical</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>Technology Research Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>ProQuest Biological Science Collection</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>PML(ProQuest Medical Library)</collection><collection>Algology Mycology and Protozoology Abstracts (Microbiology C)</collection><collection>ProQuest Biological Science Journals</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Acta pharmacologica Sinica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Yan, Jun</au><au>Tsai, Sophia Y</au><au>Tsai, Ming-jer</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>SRC-3/AIB1- transcriptional coactivator in oncogenesis</atitle><jtitle>Acta pharmacologica Sinica</jtitle><stitle>Acta Pharmacol Sin</stitle><addtitle>Acta Pharmacologica Sinica</addtitle><date>2006-04-01</date><risdate>2006</risdate><volume>27</volume><issue>4</issue><spage>387</spage><epage>394</epage><pages>387-394</pages><issn>1671-4083</issn><eissn>1745-7254</eissn><abstract>Steroid receptor coactivator-3 （SRC-3, also known as NCoA3, AIB 1, p/CIP, RAC3, ACTR, and TRAM 1）, localized on a frequently amplified region, 20q12, has been associated with multiple cancers, including breast, gastric and prostate cancers. Although SRC-3 has been implicated as an oncogene, compelling evidence has only recently emerged implicating it as a causal factor in the genesis of human cancers. Here, we summarize recent evidence that indicates aberrant SRC-3 expression is important in hormone-sensitive and -insensitive human cancers.</abstract><cop>London</cop><pub>Nature Publishing Group UK</pub><pmid>16539836</pmid><doi>10.1111/j.1745-7254.2006.00315.x</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1671-4083 |
| ispartof | Acta pharmacologica Sinica, 2006-04, Vol.27 (4), p.387-394 |
| issn | 1671-4083 1745-7254 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67751868 |
| source | Wiley-Blackwell Journals; MEDLINE; Alma/SFX Local Collection; Free Full-Text Journals in Chemistry |
| subjects | AIB1 Animals Biomedical and Life Sciences Biomedicine Breast Neoplasms - metabolism Breast Neoplasms - pathology Cell Proliferation Cell Survival Histone Acetyltransferases - chemistry Histone Acetyltransferases - genetics Histone Acetyltransferases - metabolism Humans Immunology Internal Medicine Male Medical Microbiology Nuclear Receptor Coactivator 3 Oncogenes Pharmacology/Toxicology Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology review Signal Transduction - physiology SRC-3 Stomach Neoplasms - metabolism Stomach Neoplasms - pathology Trans-Activators - chemistry Trans-Activators - genetics Trans-Activators - metabolism Transcription Factors - metabolism Vaccine 信号转导 共激活剂 肿瘤形成 |
| title | SRC-3/AIB1- transcriptional coactivator in oncogenesis |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T06%3A10%3A29IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=SRC-3/AIB1-%20transcriptional%20coactivator%20in%20oncogenesis&rft.jtitle=Acta%20pharmacologica%20Sinica&rft.au=Yan,%20Jun&rft.date=2006-04-01&rft.volume=27&rft.issue=4&rft.spage=387&rft.epage=394&rft.pages=387-394&rft.issn=1671-4083&rft.eissn=1745-7254&rft_id=info:doi/10.1111/j.1745-7254.2006.00315.x&rft_dat=%3Cproquest_pubme%3E67751868%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=213056833&rft_id=info:pmid/16539836&rft_cqvip_id=21532959&rfr_iscdi=true |