Seronegative Secondary Syphilis in 2 Patients Coinfected With Human Immunodeficiency Virus

Kingston et al detail two case reports on seronegative secondary syphilis in patients coinfected with human immudodefiency virus. Treponema pallidum is a fastidious organism that does not grow in routine laboratory cultures. Therefore, in immunocompetent patients, diagnosis of secondary syphilis rel...

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Veröffentlicht in:Archives of dermatology (1960) 2005-04, Vol.141 (4), p.431-433
Hauptverfasser: Kingston, Adean A, Vujevich, Justin, Shapiro, Michael, Hivnor, Chad M, Jukic, Drazen M, Junkins-Hopkins, Jacqueline M, Jih, Debra M, Kostman, Jay R, James, William D
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container_end_page 433
container_issue 4
container_start_page 431
container_title Archives of dermatology (1960)
container_volume 141
creator Kingston, Adean A
Vujevich, Justin
Shapiro, Michael
Hivnor, Chad M
Jukic, Drazen M
Junkins-Hopkins, Jacqueline M
Jih, Debra M
Kostman, Jay R
James, William D
description Kingston et al detail two case reports on seronegative secondary syphilis in patients coinfected with human immudodefiency virus. Treponema pallidum is a fastidious organism that does not grow in routine laboratory cultures. Therefore, in immunocompetent patients, diagnosis of secondary syphilis relies largely on nontreponemal serologic tests such as the RPR or the Venereal Disease Research Laboratory that measure serum IgG and IgM antibody reactivity to a cardiolipin-cholesterol-lecithin antigen.
doi_str_mv 10.1001/archderm.141.4.431
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Treponema pallidum is a fastidious organism that does not grow in routine laboratory cultures. 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Treponema pallidum is a fastidious organism that does not grow in routine laboratory cultures. Therefore, in immunocompetent patients, diagnosis of secondary syphilis relies largely on nontreponemal serologic tests such as the RPR or the Venereal Disease Research Laboratory that measure serum IgG and IgM antibody reactivity to a cardiolipin-cholesterol-lecithin antigen.</abstract><cop>Chicago, IL</cop><pub>American Medical Association</pub><pmid>15837859</pmid><doi>10.1001/archderm.141.4.431</doi><tpages>3</tpages></addata></record>
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subjects Adult
AIDS-Related Opportunistic Infections - drug therapy
AIDS-Related Opportunistic Infections - pathology
Anti-HIV Agents - therapeutic use
Bacterial diseases
Bacterial diseases of the genital system
Biological and medical sciences
Biopsy, Needle
Dermatology
Disease
Drug Therapy, Combination
Follow-Up Studies
HIV
Human bacterial diseases
Human immunodeficiency virus
Human immunodeficiency virus 2
Human viral diseases
Humans
Immunohistochemistry
Infections
Infectious diseases
Male
Medical diagnosis
Medical sciences
Middle Aged
Penicillin G - therapeutic use
Risk Assessment
Severity of Illness Index
Skin
Syphilis - diagnosis
Syphilis - drug therapy
Syphilis Serodiagnosis
Treatment Outcome
Treponema pallidum
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
title Seronegative Secondary Syphilis in 2 Patients Coinfected With Human Immunodeficiency Virus
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