Seronegative Secondary Syphilis in 2 Patients Coinfected With Human Immunodeficiency Virus
Kingston et al detail two case reports on seronegative secondary syphilis in patients coinfected with human immudodefiency virus. Treponema pallidum is a fastidious organism that does not grow in routine laboratory cultures. Therefore, in immunocompetent patients, diagnosis of secondary syphilis rel...
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Veröffentlicht in: | Archives of dermatology (1960) 2005-04, Vol.141 (4), p.431-433 |
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container_title | Archives of dermatology (1960) |
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creator | Kingston, Adean A Vujevich, Justin Shapiro, Michael Hivnor, Chad M Jukic, Drazen M Junkins-Hopkins, Jacqueline M Jih, Debra M Kostman, Jay R James, William D |
description | Kingston et al detail two case reports on seronegative secondary syphilis in patients coinfected with human immudodefiency virus. Treponema pallidum is a fastidious organism that does not grow in routine laboratory cultures. Therefore, in immunocompetent patients, diagnosis of secondary syphilis relies largely on nontreponemal serologic tests such as the RPR or the Venereal Disease Research Laboratory that measure serum IgG and IgM antibody reactivity to a cardiolipin-cholesterol-lecithin antigen. |
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Treponema pallidum is a fastidious organism that does not grow in routine laboratory cultures. Therefore, in immunocompetent patients, diagnosis of secondary syphilis relies largely on nontreponemal serologic tests such as the RPR or the Venereal Disease Research Laboratory that measure serum IgG and IgM antibody reactivity to a cardiolipin-cholesterol-lecithin antigen.</description><identifier>ISSN: 0003-987X</identifier><identifier>ISSN: 2168-6068</identifier><identifier>EISSN: 1538-3652</identifier><identifier>EISSN: 2168-6084</identifier><identifier>DOI: 10.1001/archderm.141.4.431</identifier><identifier>PMID: 15837859</identifier><identifier>CODEN: ARDEAC</identifier><language>eng</language><publisher>Chicago, IL: American Medical Association</publisher><subject>Adult ; AIDS-Related Opportunistic Infections - drug therapy ; AIDS-Related Opportunistic Infections - pathology ; Anti-HIV Agents - therapeutic use ; Bacterial diseases ; Bacterial diseases of the genital system ; Biological and medical sciences ; Biopsy, Needle ; Dermatology ; Disease ; Drug Therapy, Combination ; Follow-Up Studies ; HIV ; Human bacterial diseases ; Human immunodeficiency virus ; Human immunodeficiency virus 2 ; Human viral diseases ; Humans ; Immunohistochemistry ; Infections ; Infectious diseases ; Male ; Medical diagnosis ; Medical sciences ; Middle Aged ; Penicillin G - therapeutic use ; Risk Assessment ; Severity of Illness Index ; Skin ; Syphilis - diagnosis ; Syphilis - drug therapy ; Syphilis Serodiagnosis ; Treatment Outcome ; Treponema pallidum ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. 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Treponema pallidum is a fastidious organism that does not grow in routine laboratory cultures. Therefore, in immunocompetent patients, diagnosis of secondary syphilis relies largely on nontreponemal serologic tests such as the RPR or the Venereal Disease Research Laboratory that measure serum IgG and IgM antibody reactivity to a cardiolipin-cholesterol-lecithin antigen.</description><subject>Adult</subject><subject>AIDS-Related Opportunistic Infections - drug therapy</subject><subject>AIDS-Related Opportunistic Infections - pathology</subject><subject>Anti-HIV Agents - therapeutic use</subject><subject>Bacterial diseases</subject><subject>Bacterial diseases of the genital system</subject><subject>Biological and medical sciences</subject><subject>Biopsy, Needle</subject><subject>Dermatology</subject><subject>Disease</subject><subject>Drug Therapy, Combination</subject><subject>Follow-Up Studies</subject><subject>HIV</subject><subject>Human bacterial diseases</subject><subject>Human immunodeficiency virus</subject><subject>Human immunodeficiency virus 2</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immunohistochemistry</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical diagnosis</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Penicillin G - therapeutic use</subject><subject>Risk Assessment</subject><subject>Severity of Illness Index</subject><subject>Skin</subject><subject>Syphilis - diagnosis</subject><subject>Syphilis - drug therapy</subject><subject>Syphilis Serodiagnosis</subject><subject>Treatment Outcome</subject><subject>Treponema pallidum</subject><subject>Viral diseases</subject><subject>Viral diseases of the lymphoid tissue and the blood. Aids</subject><issn>0003-987X</issn><issn>2168-6068</issn><issn>1538-3652</issn><issn>2168-6084</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqF0c9rFDEUB_AgFrut_gF6kCDU26z5NUnmKEtrCwWFLSpewtv8cFNmMttkRtj_vpFdLXjxlMP7vMfL-yL0hpIlJYR-gGy3zudhSQVdiqXg9Bla0JbrhsuWPUcLQghvOq2-n6KzUu5rD9OavUCntNVc6bZboB9rn8fkf8IUf3m89nZMDvIer_e7bexjwTFhhr_Usk9TwasxpuDt5B3-Fqctvp4HSPhmGOY0Oh-irczu8deY5_ISnQToi391fM_R3dXl3eq6uf386Wb18bYBQdTUcL1xVtlOEAHgSCAAEDZaSAlBeSekI6CC1h3b6M61OgTLgvdSCgdBAj9H7w9jd3l8mH2ZzBCL9X0PyY9zMVKpltTb_BcyQjsuJKvw3T_wfpxzqn8wjHNKO9XpitgB2TyWkn0wuxyHejpDifkdj_kTj6nxGGEOK7w9Tp43g3dPLcc8Krg4AigW-pAh2VienFRUci2qe31wMMDfKq_ra8ofAVmqo-A</recordid><startdate>20050401</startdate><enddate>20050401</enddate><creator>Kingston, Adean A</creator><creator>Vujevich, Justin</creator><creator>Shapiro, Michael</creator><creator>Hivnor, Chad M</creator><creator>Jukic, Drazen M</creator><creator>Junkins-Hopkins, Jacqueline M</creator><creator>Jih, Debra M</creator><creator>Kostman, Jay R</creator><creator>James, William D</creator><general>American Medical Association</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7QL</scope><scope>7U9</scope><scope>C1K</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20050401</creationdate><title>Seronegative Secondary Syphilis in 2 Patients Coinfected With Human Immunodeficiency Virus</title><author>Kingston, Adean A ; Vujevich, Justin ; Shapiro, Michael ; Hivnor, Chad M ; Jukic, Drazen M ; Junkins-Hopkins, Jacqueline M ; Jih, Debra M ; Kostman, Jay R ; James, William D</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-a407t-38bdc7c9404aad0f0aaafb8466af7ed46d0a7f8892b89d58ffc2fee664daf6a3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>AIDS-Related Opportunistic Infections - drug therapy</topic><topic>AIDS-Related Opportunistic Infections - pathology</topic><topic>Anti-HIV Agents - therapeutic use</topic><topic>Bacterial diseases</topic><topic>Bacterial diseases of the genital system</topic><topic>Biological and medical sciences</topic><topic>Biopsy, Needle</topic><topic>Dermatology</topic><topic>Disease</topic><topic>Drug Therapy, Combination</topic><topic>Follow-Up Studies</topic><topic>HIV</topic><topic>Human bacterial diseases</topic><topic>Human immunodeficiency virus</topic><topic>Human immunodeficiency virus 2</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Immunohistochemistry</topic><topic>Infections</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Medical diagnosis</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Penicillin G - therapeutic use</topic><topic>Risk Assessment</topic><topic>Severity of Illness Index</topic><topic>Skin</topic><topic>Syphilis - diagnosis</topic><topic>Syphilis - drug therapy</topic><topic>Syphilis Serodiagnosis</topic><topic>Treatment Outcome</topic><topic>Treponema pallidum</topic><topic>Viral diseases</topic><topic>Viral diseases of the lymphoid tissue and the blood. Aids</topic><toplevel>online_resources</toplevel><creatorcontrib>Kingston, Adean A</creatorcontrib><creatorcontrib>Vujevich, Justin</creatorcontrib><creatorcontrib>Shapiro, Michael</creatorcontrib><creatorcontrib>Hivnor, Chad M</creatorcontrib><creatorcontrib>Jukic, Drazen M</creatorcontrib><creatorcontrib>Junkins-Hopkins, Jacqueline M</creatorcontrib><creatorcontrib>Jih, Debra M</creatorcontrib><creatorcontrib>Kostman, Jay R</creatorcontrib><creatorcontrib>James, William D</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>Bacteriology Abstracts (Microbiology B)</collection><collection>Virology and AIDS Abstracts</collection><collection>Environmental Sciences and Pollution Management</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of dermatology (1960)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kingston, Adean A</au><au>Vujevich, Justin</au><au>Shapiro, Michael</au><au>Hivnor, Chad M</au><au>Jukic, Drazen M</au><au>Junkins-Hopkins, Jacqueline M</au><au>Jih, Debra M</au><au>Kostman, Jay R</au><au>James, William D</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Seronegative Secondary Syphilis in 2 Patients Coinfected With Human Immunodeficiency Virus</atitle><jtitle>Archives of dermatology (1960)</jtitle><addtitle>Arch Dermatol</addtitle><date>2005-04-01</date><risdate>2005</risdate><volume>141</volume><issue>4</issue><spage>431</spage><epage>433</epage><pages>431-433</pages><issn>0003-987X</issn><issn>2168-6068</issn><eissn>1538-3652</eissn><eissn>2168-6084</eissn><coden>ARDEAC</coden><abstract>Kingston et al detail two case reports on seronegative secondary syphilis in patients coinfected with human immudodefiency virus. Treponema pallidum is a fastidious organism that does not grow in routine laboratory cultures. Therefore, in immunocompetent patients, diagnosis of secondary syphilis relies largely on nontreponemal serologic tests such as the RPR or the Venereal Disease Research Laboratory that measure serum IgG and IgM antibody reactivity to a cardiolipin-cholesterol-lecithin antigen.</abstract><cop>Chicago, IL</cop><pub>American Medical Association</pub><pmid>15837859</pmid><doi>10.1001/archderm.141.4.431</doi><tpages>3</tpages></addata></record> |
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subjects | Adult AIDS-Related Opportunistic Infections - drug therapy AIDS-Related Opportunistic Infections - pathology Anti-HIV Agents - therapeutic use Bacterial diseases Bacterial diseases of the genital system Biological and medical sciences Biopsy, Needle Dermatology Disease Drug Therapy, Combination Follow-Up Studies HIV Human bacterial diseases Human immunodeficiency virus Human immunodeficiency virus 2 Human viral diseases Humans Immunohistochemistry Infections Infectious diseases Male Medical diagnosis Medical sciences Middle Aged Penicillin G - therapeutic use Risk Assessment Severity of Illness Index Skin Syphilis - diagnosis Syphilis - drug therapy Syphilis Serodiagnosis Treatment Outcome Treponema pallidum Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids |
title | Seronegative Secondary Syphilis in 2 Patients Coinfected With Human Immunodeficiency Virus |
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