Therapeutic effect of surfactant protein D in allergic inflammation of mite-sensitized mice

Summary Background Surfactant protein D (SP‐D) is involved in the innate immunity within the lung and may have important roles in modulating the inflammatory process of asthma. Objective To examine the potential immunomodulating role of SP‐D on the allergic response in mice, and its interaction with...

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Veröffentlicht in:	Clinical and experimental allergy 2005-04, Vol.35 (4), p.515-521
Hauptverfasser:	Liu, C.-F., Chen, Y.-L., Shieh, C.-C., Yu, C.-K., Reid, K. B. M., Wang, J.-Y.
Format:	Artikel
Sprache:	eng
Schlagworte:	Allergens - immunology Allergic diseases alveolar macrophage Animals Anti-Inflammatory Agents - immunology Antigens, Dermatophagoides - immunology asthma murine model Biological and medical sciences Biological Products - immunology Bronchoalveolar Lavage Fluid - immunology Budesonide - immunology Chemokine CCL11 Chemokines, CC - immunology Chemotactic Factors, Eosinophil - immunology Eosinophils - immunology Fundamental and applied biological sciences. Psychology Fundamental immunology Immunopathology Interferon-gamma - immunology Interleukin-4 - immunology Interleukin-5 - immunology Lipopolysaccharides - immunology Macrophages, Alveolar - immunology Medical sciences Mice Mice, Inbred BALB C Nitric Oxide - biosynthesis Pulmonary Surfactant-Associated Protein D - immunology Pulmonary Surfactant-Associated Protein D - therapeutic use Pulmonary Surfactants - immunology Pulmonary Surfactants - therapeutic use Recombinant Proteins - immunology Recombinant Proteins - therapeutic use Respiratory Hypersensitivity - drug therapy Respiratory Hypersensitivity - immunology surfactant protein D Tumor Necrosis Factor-alpha - immunology
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