Antiangiogenic and Vascular-Targeting Activity of the Microtubule-Destabilizing trans-Resveratrol Derivative 3,5,4′-Trimethoxystilbene

Neovascularization plays an important role in neoplasia and angioproliferative diseases. Two major modalities have been developed so far to affect neovascularization: its prevention by antiangiogenic compounds, and immature vessel disruption by vascular-targeting agents. trans-Resveratrol, found in...

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Veröffentlicht in:	Molecular pharmacology 2005-05, Vol.67 (5), p.1451-1459
Hauptverfasser:	Belleri, Mirella, Ribatti, Domenico, Nicoli, Stefania, Cotelli, Franco, Forti, Luca, Vannini, Vanio, Stivala, Lucia Anna, Presta, Marco
Format:	Artikel
Sprache:	eng
Schlagworte:	Angiogenesis Inhibitors - chemistry Angiogenesis Inhibitors - pharmacology Animals Aorta - cytology Aorta - drug effects Aorta - physiology Cell Line, Transformed Cell Proliferation - drug effects Chickens Dose-Response Relationship, Drug Humans Male Mice Mice, Inbred BALB C Microtubules - drug effects Microtubules - physiology Rats Rats, Inbred F344 Stilbenes - chemistry Stilbenes - pharmacology Zebrafish
Online-Zugang:	Volltext
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