Mechanism of cell death induced by cationic dendrimers in RAW 264.7 murine macrophage-like cells

Cationic dendrimers possess attractive nano‐sized architectures that make them suitable as targeted drug/gene delivery systems. However, very little is known about their mechanisms of cell death in cellular systems. In the current study, the apoptotic and necrotic effects of starburst polyamidoamine...

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Veröffentlicht in:	Journal of pharmacy and pharmacology 2005-04, Vol.57 (4), p.489-495
Hauptverfasser:	Kuo, Jung-hua Steven, Jan, Ming-shiou, Chiu, Hsuan Wen
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Chloromethyl Ketones - pharmacology Animals Apoptosis Caspase Inhibitors Cations Cell Line Cell Survival - drug effects Dendrimers DNA - analysis DNA Fragmentation Drug Delivery Systems L-Lactate Dehydrogenase - biosynthesis Macrophages - drug effects Macrophages - pathology Mice Nanostructures Necrosis Polyamines - pharmacology Polypropylenes - pharmacology
Online-Zugang:	Volltext
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