Adenosinergic Modulation of Ventilation in Obese Zucker Rats

OBJECTIVES: The goal of our study was to determine whether altered adenosinergic mechanisms contribute to the depressed ventilatory response observed in obese Zucker rats. RESEARCH METHODS AND PROCEDURES: Eight lean and eight obese Zucker rats were studied at 7 to 8 weeks of age. Ventilation ([Formu...

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Veröffentlicht in:	Obesity (Silver Spring, Md.) Md.), 2005-03, Vol.13 (3), p.545-555
Hauptverfasser:	Lee, Shin-Da, Nakano, Hitoshi, Farkas, Gaspar A
Format:	Artikel
Sprache:	eng
Schlagworte:	8‐(p‐sulfophenyl)‐theophylline adenosine Adenosine - antagonists & inhibitors Adenosine - physiology aminophylline Aminophylline - pharmacology animal models Animals beta-adrenergic antagonists Carbon Dioxide - administration & dosage gonadotropin release Hypercapnia Hypoxia Male obesity Obesity - physiopathology overweight Oxygen - administration & dosage Oxygen Consumption Rats Rats, Zucker respiration Respiration - drug effects theophylline Theophylline - analogs & derivatives Theophylline - pharmacology
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