Life quality assessment among patients with atopic eczema
Summary Background Quantification of quality of life (QoL) related to disease severity is important in patients with atopic eczema (AE), because the assessment provides additional information to the traditional objective clinical scoring systems. Objectives To measure health‐related QoL (HRQoL) in...
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| Veröffentlicht in: | British journal of dermatology (1951) 2006-04, Vol.154 (4), p.719-725 |
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| container_title | British journal of dermatology (1951) |
| container_volume | 154 |
| creator | Holm, E.A. Wulf, H.C. Stegmann, H. Jemec, G.B.E. |
| description | Summary
Background Quantification of quality of life (QoL) related to disease severity is important in patients with atopic eczema (AE), because the assessment provides additional information to the traditional objective clinical scoring systems.
Objectives To measure health‐related QoL (HRQoL) in patients with AE; to analyse discriminant, divergent and convergent validity by examining the association between various QoL methods; and to examine the association between disease severity assessed by an objective Severity Scoring of Atopic Dermatitis (SCORAD) and QoL.
Methods HRQoL was assessed at two visits at a 6‐monthly interval in 101 patients with AE and 30 controls with one dermatology‐specific questionnaire [Dermatology Life Quality Index (DLQI) or Children's DLQI (CDLQI)], one generic instrument (SF‐36) and three visual analogue scales (VASs) of severity and pruritus. Objective SCORAD was used to measure disease severity.
Results Patients with AE had significantly lower QoL than healthy controls and the general population. DLQI /CDLQI, pruritus, and patient and investigator overall assessment of eczema severity were significantly (P |
| doi_str_mv | 10.1111/j.1365-2133.2005.07050.x |
| format | Article |
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Background Quantification of quality of life (QoL) related to disease severity is important in patients with atopic eczema (AE), because the assessment provides additional information to the traditional objective clinical scoring systems.
Objectives To measure health‐related QoL (HRQoL) in patients with AE; to analyse discriminant, divergent and convergent validity by examining the association between various QoL methods; and to examine the association between disease severity assessed by an objective Severity Scoring of Atopic Dermatitis (SCORAD) and QoL.
Methods HRQoL was assessed at two visits at a 6‐monthly interval in 101 patients with AE and 30 controls with one dermatology‐specific questionnaire [Dermatology Life Quality Index (DLQI) or Children's DLQI (CDLQI)], one generic instrument (SF‐36) and three visual analogue scales (VASs) of severity and pruritus. Objective SCORAD was used to measure disease severity.
Results Patients with AE had significantly lower QoL than healthy controls and the general population. DLQI /CDLQI, pruritus, and patient and investigator overall assessment of eczema severity were significantly (P < 0·0001) and positively correlated with SCORAD, while the generic questionnaire showed only poor correlation. A gender difference was found for the mental component score of SF‐36 (P = 0·019).
Conclusions AE has an impact on HRQoL. Patients' mental health, social functioning and role emotional functioning seem to be more affected than physical functioning. A simple VAS score of patients' assessment of disease severity showed the highest and most significant correlations with most of the HRQoL methods used. There is evidence to support the ability of patients with AE to make an accurate determination of their disease severity and QoL.</description><identifier>ISSN: 0007-0963</identifier><identifier>EISSN: 1365-2133</identifier><identifier>DOI: 10.1111/j.1365-2133.2005.07050.x</identifier><identifier>PMID: 16536816</identifier><identifier>CODEN: BJDEAZ</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adolescent ; Adult ; Aged ; Allergic diseases ; atopic eczema/dermatitis ; Biological and medical sciences ; Child ; Child, Preschool ; Children's Dermatology Life Quality Index ; Dermatitis, Atopic - physiopathology ; Dermatitis, Atopic - psychology ; Dermatitis, Atopic - rehabilitation ; Dermatology ; Dermatology Life Quality Index ; disease quantification ; Female ; Health Status Indicators ; Humans ; Immunopathology ; Male ; Medical sciences ; Middle Aged ; Psychometrics ; Quality of Life ; Severity of Illness Index ; SF-36 ; Skin allergic diseases. Stinging insect allergies</subject><ispartof>British journal of dermatology (1951), 2006-04, Vol.154 (4), p.719-725</ispartof><rights>2006 INIST-CNRS</rights><rights>Copyright Blackwell Publishing Apr 2006</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4130-b4ff7388dfba6b47e00753f7b6c1230f6cf84f959da1e854d63691ec6bb04b973</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1365-2133.2005.07050.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1365-2133.2005.07050.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>314,776,780,1411,27901,27902,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=17585748$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16536816$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Holm, E.A.</creatorcontrib><creatorcontrib>Wulf, H.C.</creatorcontrib><creatorcontrib>Stegmann, H.</creatorcontrib><creatorcontrib>Jemec, G.B.E.</creatorcontrib><title>Life quality assessment among patients with atopic eczema</title><title>British journal of dermatology (1951)</title><addtitle>Br J Dermatol</addtitle><description>Summary
Background Quantification of quality of life (QoL) related to disease severity is important in patients with atopic eczema (AE), because the assessment provides additional information to the traditional objective clinical scoring systems.
Objectives To measure health‐related QoL (HRQoL) in patients with AE; to analyse discriminant, divergent and convergent validity by examining the association between various QoL methods; and to examine the association between disease severity assessed by an objective Severity Scoring of Atopic Dermatitis (SCORAD) and QoL.
Methods HRQoL was assessed at two visits at a 6‐monthly interval in 101 patients with AE and 30 controls with one dermatology‐specific questionnaire [Dermatology Life Quality Index (DLQI) or Children's DLQI (CDLQI)], one generic instrument (SF‐36) and three visual analogue scales (VASs) of severity and pruritus. Objective SCORAD was used to measure disease severity.
Results Patients with AE had significantly lower QoL than healthy controls and the general population. DLQI /CDLQI, pruritus, and patient and investigator overall assessment of eczema severity were significantly (P < 0·0001) and positively correlated with SCORAD, while the generic questionnaire showed only poor correlation. A gender difference was found for the mental component score of SF‐36 (P = 0·019).
Conclusions AE has an impact on HRQoL. Patients' mental health, social functioning and role emotional functioning seem to be more affected than physical functioning. A simple VAS score of patients' assessment of disease severity showed the highest and most significant correlations with most of the HRQoL methods used. There is evidence to support the ability of patients with AE to make an accurate determination of their disease severity and QoL.</description><subject>Adolescent</subject><subject>Adult</subject><subject>Aged</subject><subject>Allergic diseases</subject><subject>atopic eczema/dermatitis</subject><subject>Biological and medical sciences</subject><subject>Child</subject><subject>Child, Preschool</subject><subject>Children's Dermatology Life Quality Index</subject><subject>Dermatitis, Atopic - physiopathology</subject><subject>Dermatitis, Atopic - psychology</subject><subject>Dermatitis, Atopic - rehabilitation</subject><subject>Dermatology</subject><subject>Dermatology Life Quality Index</subject><subject>disease quantification</subject><subject>Female</subject><subject>Health Status Indicators</subject><subject>Humans</subject><subject>Immunopathology</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Psychometrics</subject><subject>Quality of Life</subject><subject>Severity of Illness Index</subject><subject>SF-36</subject><subject>Skin allergic diseases. Stinging insect allergies</subject><issn>0007-0963</issn><issn>1365-2133</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpdkctOwzAQRS0EglL4BRQhwS7Brl_JggUUKI8KJChiaTmuDS55tHGitnw9TltAwht7NGfmzvgCECAYIX_OJhHCjIY9hHHUg5BGkEMKo8UW6PwmtkEHQshDmDC8B_adm0CIsMd2wR5iFLMYsQ5IhtboYNbIzNbLQDqnnct1UQcyL4v3YCpr6yMXzG39Eci6nFoVaPWlc3kAdozMnD7c3F3wenM96t-Gw6fBXf9iGCri5cKUGMNxHI9NKllKuPYzUWx4yhTqYWiYMjExCU3GEumYkjHDLEFasTSFJE047oLTdd9pVc4a7WqRW6d0lslCl40TjHNCIYk9ePwPnJRNVfjZRK9dHWHadjvaQE2a67GYVjaX1VL8_IgHTjaAdEpmppKFsu6P4zSmfKV2vubmNtPLvzwUrUNiIlojRGtEq07FyiGxEJf3V-3L14freutqvfitl9Wn3whzKt4eB-Ke9x9eRs8PguBvfPORHg</recordid><startdate>200604</startdate><enddate>200604</enddate><creator>Holm, E.A.</creator><creator>Wulf, H.C.</creator><creator>Stegmann, H.</creator><creator>Jemec, G.B.E.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><general>Oxford University Press</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7T5</scope><scope>H94</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7X8</scope></search><sort><creationdate>200604</creationdate><title>Life quality assessment among patients with atopic eczema</title><author>Holm, E.A. ; Wulf, H.C. ; Stegmann, H. ; Jemec, G.B.E.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4130-b4ff7388dfba6b47e00753f7b6c1230f6cf84f959da1e854d63691ec6bb04b973</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Aged</topic><topic>Allergic diseases</topic><topic>atopic eczema/dermatitis</topic><topic>Biological and medical sciences</topic><topic>Child</topic><topic>Child, Preschool</topic><topic>Children's Dermatology Life Quality Index</topic><topic>Dermatitis, Atopic - physiopathology</topic><topic>Dermatitis, Atopic - psychology</topic><topic>Dermatitis, Atopic - rehabilitation</topic><topic>Dermatology</topic><topic>Dermatology Life Quality Index</topic><topic>disease quantification</topic><topic>Female</topic><topic>Health Status Indicators</topic><topic>Humans</topic><topic>Immunopathology</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Psychometrics</topic><topic>Quality of Life</topic><topic>Severity of Illness Index</topic><topic>SF-36</topic><topic>Skin allergic diseases. Stinging insect allergies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Holm, E.A.</creatorcontrib><creatorcontrib>Wulf, H.C.</creatorcontrib><creatorcontrib>Stegmann, H.</creatorcontrib><creatorcontrib>Jemec, G.B.E.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>Immunology Abstracts</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>MEDLINE - Academic</collection><jtitle>British journal of dermatology (1951)</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Holm, E.A.</au><au>Wulf, H.C.</au><au>Stegmann, H.</au><au>Jemec, G.B.E.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Life quality assessment among patients with atopic eczema</atitle><jtitle>British journal of dermatology (1951)</jtitle><addtitle>Br J Dermatol</addtitle><date>2006-04</date><risdate>2006</risdate><volume>154</volume><issue>4</issue><spage>719</spage><epage>725</epage><pages>719-725</pages><issn>0007-0963</issn><eissn>1365-2133</eissn><coden>BJDEAZ</coden><abstract>Summary
Background Quantification of quality of life (QoL) related to disease severity is important in patients with atopic eczema (AE), because the assessment provides additional information to the traditional objective clinical scoring systems.
Objectives To measure health‐related QoL (HRQoL) in patients with AE; to analyse discriminant, divergent and convergent validity by examining the association between various QoL methods; and to examine the association between disease severity assessed by an objective Severity Scoring of Atopic Dermatitis (SCORAD) and QoL.
Methods HRQoL was assessed at two visits at a 6‐monthly interval in 101 patients with AE and 30 controls with one dermatology‐specific questionnaire [Dermatology Life Quality Index (DLQI) or Children's DLQI (CDLQI)], one generic instrument (SF‐36) and three visual analogue scales (VASs) of severity and pruritus. Objective SCORAD was used to measure disease severity.
Results Patients with AE had significantly lower QoL than healthy controls and the general population. DLQI /CDLQI, pruritus, and patient and investigator overall assessment of eczema severity were significantly (P < 0·0001) and positively correlated with SCORAD, while the generic questionnaire showed only poor correlation. A gender difference was found for the mental component score of SF‐36 (P = 0·019).
Conclusions AE has an impact on HRQoL. Patients' mental health, social functioning and role emotional functioning seem to be more affected than physical functioning. A simple VAS score of patients' assessment of disease severity showed the highest and most significant correlations with most of the HRQoL methods used. There is evidence to support the ability of patients with AE to make an accurate determination of their disease severity and QoL.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>16536816</pmid><doi>10.1111/j.1365-2133.2005.07050.x</doi><tpages>7</tpages></addata></record> |
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| ispartof | British journal of dermatology (1951), 2006-04, Vol.154 (4), p.719-725 |
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| source | Oxford University Press Journals All Titles (1996-Current); MEDLINE; Wiley Online Library Journals Frontfile Complete |
| subjects | Adolescent Adult Aged Allergic diseases atopic eczema/dermatitis Biological and medical sciences Child Child, Preschool Children's Dermatology Life Quality Index Dermatitis, Atopic - physiopathology Dermatitis, Atopic - psychology Dermatitis, Atopic - rehabilitation Dermatology Dermatology Life Quality Index disease quantification Female Health Status Indicators Humans Immunopathology Male Medical sciences Middle Aged Psychometrics Quality of Life Severity of Illness Index SF-36 Skin allergic diseases. Stinging insect allergies |
| title | Life quality assessment among patients with atopic eczema |
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