Hormonal regulation of hepatic multidrug resistance-associated protein 2 (Abcc2) primarily involves the pattern of growth hormone secretion

Biliary excretion is the rate-limiting step in transfer of bilirubin, other organic anions, and xenobiotics across the liver. Multidrug resistance-associated protein 2 (Mrp2, Abcc2) is the major transporter for conjugated endo- and xenobiotic-conjugated compounds into bile. Hormones regulate bilirub...

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Veröffentlicht in:	American journal of physiology: Gastrointestinal and liver physiology 2006-04, Vol.290 (4), p.G595-G608
Hauptverfasser:	Simon, Francis R, Iwahashi, Mieko, Hu, Ling-Jia, Qadri, Ishtiaq, Arias, Irwin M, Ortiz, Daniel, Dahl, Rolf, Sutherland, Eileen
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals ATP-Binding Cassette Transporters - metabolism Female Gene Expression Regulation - physiology Gonadal Steroid Hormones - metabolism Growth Hormone - secretion Liver - metabolism Male Rats Rats, Sprague-Dawley Sex Factors
Online-Zugang:	Volltext
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