Somatosensory cortical atrophy after spinal cord injury : A voxel-based morphometry study

The authors used voxel-based morphometry to compare sensorimotor cortical gray and white matter volume on structural MR images of a group of 17 individuals with cervical spinal cord injury (SCI) and a group of 17 healthy subjects. SCI subjects had reduced gray matter volume bilaterally in primary so...

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Veröffentlicht in:	Neurology 2006-03, Vol.66 (5), p.762-764
Hauptverfasser:	JURKIEWICZ, M. T, CRAWLEY, A. P, VERRIER, M. C, FEHLINGS, M. G, MIKULIS, D. J
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Atrophy Behavior Biological and medical sciences Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Female Humans Injuries of the nervous system and the skull. Diseases due to physical agents Male Medical sciences Motor Activity Neurology Reference Values Somatosensory Cortex - pathology Spinal Cord Injuries - pathology Spinal Cord Injuries - physiopathology Spinal Cord Injuries - psychology Traumas. Diseases due to physical agents
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Zusammenfassung:	The authors used voxel-based morphometry to compare sensorimotor cortical gray and white matter volume on structural MR images of a group of 17 individuals with cervical spinal cord injury (SCI) and a group of 17 healthy subjects. SCI subjects had reduced gray matter volume bilaterally in primary somatosensory cortex (p < 0.001). These findings suggest that the somatosensory cortex of the human brain atrophies after SCI.
ISSN:	0028-3878 1526-632X
DOI:	10.1212/01.wnl.0000201276.28141.40