The 460Trp allele of α-adducin increases carotid intima–media thickness in young adult males

BACKGROUNDThe 460Trp allele of the α-adducin gene (ADD1), which is involved in a form of salt-sensitive hypertension, has been associated with patterns of target organ damage. OBJECTIVESAs carotid artery intima–media thickness (IMT) largely depends upon unknown genetic factors, besides being associa...

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