Syntheses of Novel Indole Lipoic Acid Derivatives and Their Antioxidant Effects on Lipid Peroxidation

The aim of the study was to examine antioxidant properties of conjugates based on indole and lipoic acid moieties. The design and syntheses of novel indole α‐lipoic acid derivatives were performed. The antioxidant properties of target compounds were investigated using rat liver microsomal, NADPH‐dep...

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Veröffentlicht in:	Archiv der Pharmazie (Weinheim) 2005-03, Vol.338 (2-3), p.67-73
Hauptverfasser:	Gurkan, A. Selen, Karabay, Arzu, Buyukbingol, Zeliha, Adejare, Adeboye, Buyukbingol, Erdem
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidant Antioxidants - chemistry Antioxidants - pharmacology Biological and medical sciences General and cellular metabolism. Vitamins Indole Indoles - chemical synthesis Indoles - chemistry Indoles - pharmacology Lipid peroxidation Lipid Peroxidation - drug effects Male Medical sciences Pharmacology. Drug treatments Rats Rats, Wistar Structure-Activity Relationship Thioctic Acid - analogs & derivatives Thioctic Acid - chemical synthesis Thioctic Acid - chemistry α-Lipoic acid
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