Role of costimulatory molecules in immune response of patients with cutaneous leishmaniasis

T cell-mediated immunity is critical in resistance against Leishmania parasites, and T cell activation requires signals provided by costimulatory molecules. Herein we evaluated the role of costimulatory molecules on cytokine production and T cell surface molecule expression by peripheral blood monon...

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Veröffentlicht in:	Microbes and infection 2005, Vol.7 (1), p.86-92
Hauptverfasser:	Favali, Cecilia, Costa, Dirceu, Afonso, Lilian, Conceição, Viviane, Rosato, Andréa, Oliveira, Fabiano, Costa, Jackson, Barral, Aldina, Barral-Netto, Manoel, Brodskyn, Claudia Ida
Format:	Artikel
Sprache:	eng
Schlagworte:	Abatacept Adult Biological and medical sciences CD28 Antigens - immunology Cells, Cultured Cutaneous leishmaniasis Cytokines Down-Regulation Female Fundamental and applied biological sciences. Psychology Humans Immunoconjugates - immunology Immunomodulation Interferon-gamma - biosynthesis Interleukin-10 - biosynthesis Leishmania Leishmaniasis, Cutaneous - blood Leishmaniasis, Cutaneous - immunology Leukocytes, Mononuclear Male Microbiology T-Lymphocytes - immunology Tumor Necrosis Factor-alpha - biosynthesis
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