Cascade Alkenyl Amination/Heck Reaction Promoted by a Bifunctional Palladium Catalyst: A Novel One-Pot Synthesis of Indoles from o-Haloanilines and Alkenyl Halides

A novel approach for the synthesis of the important indole ring is described. Indoles are obtained from o‐bromoanilines and alkenyl halides in a Pd‐catalyzed cascade process that involves an alkenyl amination followed by an intramolecular Heck reaction. The overall process represents the first examp...

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Veröffentlicht in:	Chemistry : a European journal 2005-04, Vol.11 (8), p.2276-2283
Hauptverfasser:	Barluenga, José, Fernández, M. Alejandro, Aznar, Fernando, Valdés, Carlos
Format:	Artikel
Sprache:	eng
Schlagworte:	amination enamines Heck reaction indoles nitrogen heterocycles palladium
Online-Zugang:	Volltext
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