CRIMEAN-CONGO HEMORRHAGIC FEVER OUTBREAK IN RAWALPINDI, PAKISTAN, FEBRUARY 2002: CONTACT TRACING AND RISK ASSESSMENT
A 25-year-old woman, later identified as index case of Crimean-Congo hemorrhagic fever (CCHF), presented to Holy Family Hospital in Rawalpindi, Pakistan with fever and generalized coagulopathy. A retrospective contact tracing was conducted to explore the modes of exposure possibly associated with tr...
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| Veröffentlicht in: | The American journal of tropical medicine and hygiene 2005-04, Vol.72 (4), p.471-473 |
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| container_title | The American journal of tropical medicine and hygiene |
| container_volume | 72 |
| creator | ATHAR, MUHAMMAD NAUMAN KHALID, MOHAMMAD ALI AHMAD, AHSAN MAQBOOL BASHIR, NAGHMAN BAQAI, HAIDER ZAIGHAM AHMAD, MASOOD BALOUCH, ABBAS HAYAT BASHIR, KAUKAB |
| description | A 25-year-old woman, later identified as index case of Crimean-Congo hemorrhagic fever (CCHF), presented to Holy Family Hospital in Rawalpindi, Pakistan with fever and generalized coagulopathy. A retrospective contact tracing was conducted to explore the modes of exposure possibly associated with transmission of CCHF infection among contacts. We traced 32 contacts of the index case and 158 contacts of secondary cases and tested them for IgG and IgM antibodies against CCHF virus by an enzyme-linked immunosorbent assay technique. According to the type of exposure, contacts were divided into five subsets: percutaneous contact with blood, blood contact to unbroken skin, cutaneous contact to non-sanguineous body fluids, physical contact with patients without body fluids contact, and close proximity without touching. Two out of four contacts who reported percutaneous exposure tested positive for antibodies to CCHF virus. We conclude that simple barrier methods and care in provision of CCHF cases may prevent transmission of this infection. |
| doi_str_mv | 10.4269/ajtmh.2005.72.471 |
| format | Article |
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A retrospective contact tracing was conducted to explore the modes of exposure possibly associated with transmission of CCHF infection among contacts. We traced 32 contacts of the index case and 158 contacts of secondary cases and tested them for IgG and IgM antibodies against CCHF virus by an enzyme-linked immunosorbent assay technique. According to the type of exposure, contacts were divided into five subsets: percutaneous contact with blood, blood contact to unbroken skin, cutaneous contact to non-sanguineous body fluids, physical contact with patients without body fluids contact, and close proximity without touching. Two out of four contacts who reported percutaneous exposure tested positive for antibodies to CCHF virus. We conclude that simple barrier methods and care in provision of CCHF cases may prevent transmission of this infection.</description><identifier>ISSN: 0002-9637</identifier><identifier>EISSN: 1476-1645</identifier><identifier>DOI: 10.4269/ajtmh.2005.72.471</identifier><identifier>PMID: 15827289</identifier><identifier>CODEN: AJTHAB</identifier><language>eng</language><publisher>Lawrence, KS: ASTMH</publisher><subject>Adult ; Biological and medical sciences ; Disease Outbreaks ; Enzyme-Linked Immunosorbent Assay ; Female ; Hemorrhagic Fever, Crimean - epidemiology ; Humans ; Infectious diseases ; Medical sciences ; Pakistan - epidemiology ; Reverse Transcriptase Polymerase Chain Reaction ; Risk Assessment</subject><ispartof>The American journal of tropical medicine and hygiene, 2005-04, Vol.72 (4), p.471-473</ispartof><rights>2005 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c433t-2caaa3eb6d40ea65a91fe8413d39698f85f07c0c29625a4e7eef6fe30cb876143</citedby></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16687346$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15827289$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>ATHAR, MUHAMMAD NAUMAN</creatorcontrib><creatorcontrib>KHALID, MOHAMMAD ALI</creatorcontrib><creatorcontrib>AHMAD, AHSAN MAQBOOL</creatorcontrib><creatorcontrib>BASHIR, NAGHMAN</creatorcontrib><creatorcontrib>BAQAI, HAIDER ZAIGHAM</creatorcontrib><creatorcontrib>AHMAD, MASOOD</creatorcontrib><creatorcontrib>BALOUCH, ABBAS HAYAT</creatorcontrib><creatorcontrib>BASHIR, KAUKAB</creatorcontrib><title>CRIMEAN-CONGO HEMORRHAGIC FEVER OUTBREAK IN RAWALPINDI, PAKISTAN, FEBRUARY 2002: CONTACT TRACING AND RISK ASSESSMENT</title><title>The American journal of tropical medicine and hygiene</title><addtitle>Am J Trop Med Hyg</addtitle><description>A 25-year-old woman, later identified as index case of Crimean-Congo hemorrhagic fever (CCHF), presented to Holy Family Hospital in Rawalpindi, Pakistan with fever and generalized coagulopathy. A retrospective contact tracing was conducted to explore the modes of exposure possibly associated with transmission of CCHF infection among contacts. We traced 32 contacts of the index case and 158 contacts of secondary cases and tested them for IgG and IgM antibodies against CCHF virus by an enzyme-linked immunosorbent assay technique. According to the type of exposure, contacts were divided into five subsets: percutaneous contact with blood, blood contact to unbroken skin, cutaneous contact to non-sanguineous body fluids, physical contact with patients without body fluids contact, and close proximity without touching. Two out of four contacts who reported percutaneous exposure tested positive for antibodies to CCHF virus. We conclude that simple barrier methods and care in provision of CCHF cases may prevent transmission of this infection.</description><subject>Adult</subject><subject>Biological and medical sciences</subject><subject>Disease Outbreaks</subject><subject>Enzyme-Linked Immunosorbent Assay</subject><subject>Female</subject><subject>Hemorrhagic Fever, Crimean - epidemiology</subject><subject>Humans</subject><subject>Infectious diseases</subject><subject>Medical sciences</subject><subject>Pakistan - epidemiology</subject><subject>Reverse Transcriptase Polymerase Chain Reaction</subject><subject>Risk Assessment</subject><issn>0002-9637</issn><issn>1476-1645</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqFkT1v2zAURYmiQeOm_QFdCi7NFDn8Eil1YxTFFmxLASW36ETQNFUrkOJUtGH031dODHjs9JZz733AAeALRmNGeHxrnnbdZkwQCseCjJnA78AIM8EDzFn4HowQQiSIORWX4KP3TwjhiGD8AVziMCKCRPEI7BKVLVKZB0mRTwo4TReFUlM5yRL4kP5IFSyW1Z1K5QxmOVTyp5w_Zvl9dgMf5SwrK5nfDNydWkr1Cw6PkO9wKKpkUsFKySTLJ1Dm91Bl5QzKskzLcpHm1SdwUZvWu8-newWWD2mVTIN5MQzLeWAZpbuAWGMMdSu-ZsgZHpoY1y5imK5pzOOojsIaCYssiTkJDXPCuZrXjiK7igTHjF6B67fel377Z-_8TneNt65tzbPb7r3mQlBKKP4viAVnSKAjiN9A22-9712tX_qmM_1fjZE-OtGvTvTRiRZED06GzNdT-X7VufU5cZIwAN9OgPHWtHVvnm3jzxznkaCMn7lN83tzaHqnfWfadqjF-nA4HOdeB_8Bn4aYHg</recordid><startdate>20050401</startdate><enddate>20050401</enddate><creator>ATHAR, MUHAMMAD NAUMAN</creator><creator>KHALID, MOHAMMAD ALI</creator><creator>AHMAD, AHSAN MAQBOOL</creator><creator>BASHIR, NAGHMAN</creator><creator>BAQAI, HAIDER ZAIGHAM</creator><creator>AHMAD, MASOOD</creator><creator>BALOUCH, ABBAS HAYAT</creator><creator>BASHIR, KAUKAB</creator><general>ASTMH</general><general>Allen Press</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7U9</scope><scope>H94</scope><scope>7X8</scope></search><sort><creationdate>20050401</creationdate><title>CRIMEAN-CONGO HEMORRHAGIC FEVER OUTBREAK IN RAWALPINDI, PAKISTAN, FEBRUARY 2002: CONTACT TRACING AND RISK ASSESSMENT</title><author>ATHAR, MUHAMMAD NAUMAN ; 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A retrospective contact tracing was conducted to explore the modes of exposure possibly associated with transmission of CCHF infection among contacts. We traced 32 contacts of the index case and 158 contacts of secondary cases and tested them for IgG and IgM antibodies against CCHF virus by an enzyme-linked immunosorbent assay technique. According to the type of exposure, contacts were divided into five subsets: percutaneous contact with blood, blood contact to unbroken skin, cutaneous contact to non-sanguineous body fluids, physical contact with patients without body fluids contact, and close proximity without touching. Two out of four contacts who reported percutaneous exposure tested positive for antibodies to CCHF virus. 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| subjects | Adult Biological and medical sciences Disease Outbreaks Enzyme-Linked Immunosorbent Assay Female Hemorrhagic Fever, Crimean - epidemiology Humans Infectious diseases Medical sciences Pakistan - epidemiology Reverse Transcriptase Polymerase Chain Reaction Risk Assessment |
| title | CRIMEAN-CONGO HEMORRHAGIC FEVER OUTBREAK IN RAWALPINDI, PAKISTAN, FEBRUARY 2002: CONTACT TRACING AND RISK ASSESSMENT |
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