Application of microbore HPLC in combination with tandem MS for the quantification of rosuvastatin in human plasma

The potential of microbore high-performance liquid chromatography (HPLC) in combination with tandem mass spectrometry (MS/MS) for the sensitive detection of rosuvastatin (Crestor™) in human plasma was investigated. Three microbore HPLC columns with internal diameters (i.d.) of 0.5, 1.0 and 2.0 mm we...

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Veröffentlicht in:	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Analytical technologies in the biomedical and life sciences, 2006-03, Vol.832 (2), p.191-196
Hauptverfasser:	Oudhoff, Kathalijne A., Sangster, Timothy, Thomas, Elizabeth, Wilson, Ian D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Analysis Analytical, structural and metabolic biochemistry Bioanalysis Biological and medical sciences Chromatography, High Pressure Liquid - methods Fluorobenzenes - blood Fundamental and applied biological sciences. Psychology General pharmacology Human plasma Humans Mass Spectrometry - methods Medical sciences Microbore HPLC Pharmacology. Drug treatments Pyrimidines - blood Rosuvastatin Rosuvastatin Calcium Sensitivity and Specificity Sulfonamides - blood
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