T‐Cell Lymphoma of the Rectum in a Patient with AIDS and Hepatitis C: A Case Report and Discussion
Primary T‐cell non‐Hodgkin's lymphoma (NHL) occurring in the context of acquired immune deficiency syndrome (AIDS) is uncommon. Here, we report and discuss such a case presenting in the rectum, and review relevant literature. Although typical in some respects, the case is, in other ways, somewh...
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| Veröffentlicht in: | The oncologist (Dayton, Ohio) Ohio), 2005-04, Vol.10 (4), p.292-298 |
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| container_title | The oncologist (Dayton, Ohio) |
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| creator | Tisdale, Gus Mahadevan, Anand Matthews, Richard H. |
| description | Primary T‐cell non‐Hodgkin's lymphoma (NHL) occurring in the context of acquired immune deficiency syndrome (AIDS) is uncommon. Here, we report and discuss such a case presenting in the rectum, and review relevant literature. Although typical in some respects, the case is, in other ways, somewhat unusual for an AIDS‐related NHL (ARL); ARL tends to be B cell and advanced stage and our case was T cell and stage IE. In addition, the patient suffered from concomitant cirrhosis related to hepatitis C. Chemotherapeutic options for ARL were limited early in the AIDS epidemic due to poor tolerability. Although this has largely been mitigated by the advent of highly active antiretroviral therapy, our patient eventually suffered complications of chemotherapy, apparently related more to his liver disease than to either his lymphoma or AIDS, that ultimately brought about his demise. |
| doi_str_mv | 10.1634/theoncologist.10-4-292 |
| format | Article |
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Here, we report and discuss such a case presenting in the rectum, and review relevant literature. Although typical in some respects, the case is, in other ways, somewhat unusual for an AIDS‐related NHL (ARL); ARL tends to be B cell and advanced stage and our case was T cell and stage IE. In addition, the patient suffered from concomitant cirrhosis related to hepatitis C. Chemotherapeutic options for ARL were limited early in the AIDS epidemic due to poor tolerability. 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| identifier | ISSN: 1083-7159 |
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| issn | 1083-7159 1549-490X |
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| source | Oxford Journals Open Access Collection; MEDLINE; Wiley Online Library Journals Frontfile Complete; EZB-FREE-00999 freely available EZB journals |
| subjects | AIDS AIDS-Related Opportunistic Infections - complications AIDS-Related Opportunistic Infections - drug therapy AIDS-Related Opportunistic Infections - physiopathology Antiretroviral Therapy, Highly Active Fatal Outcome Hepatitis C Hepatitis C - complications Hepatitis C - physiopathology Humans Lymphoma, AIDS-Related - diagnosis Lymphoma, AIDS-Related - drug therapy Lymphoma, AIDS-Related - physiopathology Lymphoma, T-Cell - diagnosis Lymphoma, T-Cell - physiopathology Male Middle Aged Multimodal treatment Rectal Neoplasms - diagnosis Rectal Neoplasms - physiopathology T‐cell lymphoma |
| title | T‐Cell Lymphoma of the Rectum in a Patient with AIDS and Hepatitis C: A Case Report and Discussion |
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