Prevalence of methylenetetrahydrofolate reductase 677T and 1298C alleles and folate status: a comparative study in Mexican, West African, and European populations

BACKGROUND: Methylenetetrahydrofolate reductase (MTHFR) 677C[rightwards arrow]T polymorphism is heterogeneously distributed worldwide, with the highest and lowest frequencies of the T allele in Mexico and Africa, respectively, and a south-to-north gradient in Europe. Distribution of MTHFR 1298A[righ...

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Veröffentlicht in:	The American journal of clinical nutrition 2006-03, Vol.83 (3), p.701-707
Hauptverfasser:	Guéant-Rodriguez, Rosa-Maria, Guéant, Jean-Louis, Debard, Renée, Thirion, Sylvie, Hong, Lu Xiao, Bronowicki, Jean-Pierre, Namour, Farès, Chabi, Nicodème W, Sanni, Ambaliou, Anello, Guido, Bosco, Paolo, Romano, Corrado, Amouzou, Emile, Arrieta, Heidy R, Sánchez, Beatríz E, Romano, Antonino, Herbeth, Bernard, Guilland, Jean-Claude, Mutchinick, Osvaldo M
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Africa, Western Alleles Biological and medical sciences blood serum Comparative studies epidemiological studies Europe Feeding. Feeding behavior Female folic acid Folic Acid - blood Fundamental and applied biological sciences. Psychology Gene Frequency Genes genetic polymorphism genomics Genotype homocysteine Homocysteine - blood Humans Male methylenetetrahydrofolate reductase Methylenetetrahydrofolate Reductase (NADPH2) - genetics Mexico Middle Aged nutritional status Polymorphism Polymorphism, Genetic Regression Analysis Vertebrates: anatomy and physiology, studies on body, several organs or systems Vitamin B Vitamin B 12 - blood vitamin B12 vitamin deficiencies young adults
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