Antibiotic production improvement in the rare actinomycete Planobispora rosea by selection of mutants resistant to the Aminoglycosides Streptomycin and Gentamycin and to Rifamycin

During a strain improvement program, spontaneous mutants with single or combined resistance to streptomycin (Strr), gentamycin (Genr) or rifamycin (Rifr) were selected from the industrial strain of Planobispora rosea, which is the producer of thiazolylpeptide GE2270. Among the mutants resistant to e...

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Veröffentlicht in:	Journal of industrial microbiology & biotechnology 2006-04, Vol.33 (4), p.283-288
Hauptverfasser:	Beltrametti, Fabrizio, Rossi, Roberta, Selva, Enrico, Marinelli, Flavia
Format:	Artikel
Sprache:	eng
Schlagworte:	Actinomycetales - drug effects Actinomycetales - genetics Actinomycetales - metabolism Anti-Bacterial Agents - biosynthesis Anti-Bacterial Agents - pharmacology Antibiotics Bacteria Biological and medical sciences Biotechnology Drug Resistance, Microbial - genetics Drug Resistance, Multiple, Bacterial - genetics Fundamental and applied biological sciences. Psychology Gentamicins - pharmacology Microbiology Mutation Rifamycins - pharmacology Spores, Bacterial - genetics Spores, Bacterial - physiology Streptomycin - pharmacology
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