The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment
Objectives: To develop a 10‐minute cognitive screening tool (Montreal Cognitive Assessment, MoCA) to assist first‐line physicians in detection of mild cognitive impairment (MCI), a clinical state that often progresses to dementia. Design: Validation study. Setting: A community clinic and an academic...
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Veröffentlicht in: | Journal of the American Geriatrics Society 2005-04, Vol.53 (4), p.695-699 |
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creator | Nasreddine, Ziad S. Phillips, Natalie A. Bédirian, Valérie Charbonneau, Simon Whitehead, Victor Collin, Isabelle Cummings, Jeffrey L. Chertkow, Howard |
description | Objectives: To develop a 10‐minute cognitive screening tool (Montreal Cognitive Assessment, MoCA) to assist first‐line physicians in detection of mild cognitive impairment (MCI), a clinical state that often progresses to dementia.
Design: Validation study.
Setting: A community clinic and an academic center.
Participants: Ninety‐four patients meeting MCI clinical criteria supported by psychometric measures, 93 patients with mild Alzheimer's disease (AD) (Mini‐Mental State Examination (MMSE) score≥17), and 90 healthy elderly controls (NC).
Measurements: The MoCA and MMSE were administered to all participants, and sensitivity and specificity of both measures were assessed for detection of MCI and mild AD.
Results: Using a cutoff score 26, the MMSE had a sensitivity of 18% to detect MCI, whereas the MoCA detected 90% of MCI subjects. In the mild AD group, the MMSE had a sensitivity of 78%, whereas the MoCA detected 100%. Specificity was excellent for both MMSE and MoCA (100% and 87%, respectively).
Conclusion: MCI as an entity is evolving and somewhat controversial. The MoCA is a brief cognitive screening tool with high sensitivity and specificity for detecting MCI as currently conceptualized in patients performing in the normal range on the MMSE. |
doi_str_mv | 10.1111/j.1532-5415.2005.53221.x |
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Design: Validation study.
Setting: A community clinic and an academic center.
Participants: Ninety‐four patients meeting MCI clinical criteria supported by psychometric measures, 93 patients with mild Alzheimer's disease (AD) (Mini‐Mental State Examination (MMSE) score≥17), and 90 healthy elderly controls (NC).
Measurements: The MoCA and MMSE were administered to all participants, and sensitivity and specificity of both measures were assessed for detection of MCI and mild AD.
Results: Using a cutoff score 26, the MMSE had a sensitivity of 18% to detect MCI, whereas the MoCA detected 90% of MCI subjects. In the mild AD group, the MMSE had a sensitivity of 78%, whereas the MoCA detected 100%. Specificity was excellent for both MMSE and MoCA (100% and 87%, respectively).
Conclusion: MCI as an entity is evolving and somewhat controversial. The MoCA is a brief cognitive screening tool with high sensitivity and specificity for detecting MCI as currently conceptualized in patients performing in the normal range on the MMSE.</description><identifier>ISSN: 0002-8614</identifier><identifier>EISSN: 1532-5415</identifier><identifier>DOI: 10.1111/j.1532-5415.2005.53221.x</identifier><identifier>PMID: 15817019</identifier><identifier>CODEN: JAGSAF</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Science Inc</publisher><subject>Aged ; Alzheimer Disease - diagnosis ; Alzheimer's ; Biological and medical sciences ; Canada ; Case-Control Studies ; Clinical assessment ; Cognition & reasoning ; Cognition Disorders - diagnosis ; cognitive assessment ; Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases ; Dementia ; Elderly people ; Female ; General aspects ; Humans ; Male ; Medical sciences ; Medical screening ; Mild cognitive disorders ; mild cognitive impairment ; MoCA ; Neurology ; Neuropsychological Tests ; Older people ; Psychometrics ; Quebec ; Reproducibility of Results ; Screening ; Sensitivity and Specificity ; Validation ; Validation studies</subject><ispartof>Journal of the American Geriatrics Society, 2005-04, Vol.53 (4), p.695-699</ispartof><rights>2005 INIST-CNRS</rights><rights>2005 by the American Geriatrics Society</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c6151-591003e60a2765836dd021c5465fcae9e867dbe87c338abc97abc5ed511887be3</citedby><cites>FETCH-LOGICAL-c6151-591003e60a2765836dd021c5465fcae9e867dbe87c338abc97abc5ed511887be3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://onlinelibrary.wiley.com/doi/pdf/10.1111%2Fj.1532-5415.2005.53221.x$$EPDF$$P50$$Gwiley$$H</linktopdf><linktohtml>$$Uhttps://onlinelibrary.wiley.com/doi/full/10.1111%2Fj.1532-5415.2005.53221.x$$EHTML$$P50$$Gwiley$$H</linktohtml><link.rule.ids>309,310,314,776,780,785,786,1411,23909,23910,25118,27901,27902,30977,45550,45551</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=16721239$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15817019$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nasreddine, Ziad S.</creatorcontrib><creatorcontrib>Phillips, Natalie A.</creatorcontrib><creatorcontrib>Bédirian, Valérie</creatorcontrib><creatorcontrib>Charbonneau, Simon</creatorcontrib><creatorcontrib>Whitehead, Victor</creatorcontrib><creatorcontrib>Collin, Isabelle</creatorcontrib><creatorcontrib>Cummings, Jeffrey L.</creatorcontrib><creatorcontrib>Chertkow, Howard</creatorcontrib><title>The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment</title><title>Journal of the American Geriatrics Society</title><addtitle>J Am Geriatr Soc</addtitle><description>Objectives: To develop a 10‐minute cognitive screening tool (Montreal Cognitive Assessment, MoCA) to assist first‐line physicians in detection of mild cognitive impairment (MCI), a clinical state that often progresses to dementia.
Design: Validation study.
Setting: A community clinic and an academic center.
Participants: Ninety‐four patients meeting MCI clinical criteria supported by psychometric measures, 93 patients with mild Alzheimer's disease (AD) (Mini‐Mental State Examination (MMSE) score≥17), and 90 healthy elderly controls (NC).
Measurements: The MoCA and MMSE were administered to all participants, and sensitivity and specificity of both measures were assessed for detection of MCI and mild AD.
Results: Using a cutoff score 26, the MMSE had a sensitivity of 18% to detect MCI, whereas the MoCA detected 90% of MCI subjects. In the mild AD group, the MMSE had a sensitivity of 78%, whereas the MoCA detected 100%. Specificity was excellent for both MMSE and MoCA (100% and 87%, respectively).
Conclusion: MCI as an entity is evolving and somewhat controversial. The MoCA is a brief cognitive screening tool with high sensitivity and specificity for detecting MCI as currently conceptualized in patients performing in the normal range on the MMSE.</description><subject>Aged</subject><subject>Alzheimer Disease - diagnosis</subject><subject>Alzheimer's</subject><subject>Biological and medical sciences</subject><subject>Canada</subject><subject>Case-Control Studies</subject><subject>Clinical assessment</subject><subject>Cognition & reasoning</subject><subject>Cognition Disorders - diagnosis</subject><subject>cognitive assessment</subject><subject>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</subject><subject>Dementia</subject><subject>Elderly people</subject><subject>Female</subject><subject>General aspects</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Medical screening</subject><subject>Mild cognitive disorders</subject><subject>mild cognitive impairment</subject><subject>MoCA</subject><subject>Neurology</subject><subject>Neuropsychological Tests</subject><subject>Older people</subject><subject>Psychometrics</subject><subject>Quebec</subject><subject>Reproducibility of Results</subject><subject>Screening</subject><subject>Sensitivity and Specificity</subject><subject>Validation</subject><subject>Validation studies</subject><issn>0002-8614</issn><issn>1532-5415</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>7QJ</sourceid><recordid>eNqNkU9vEzEQxVcIRNPCV0AWEpzYxWOv114OSCFqQmkLEglwQpbjnRSH_RPsDaTfHm8TtYgL-GB7NL_35PFLEgI0g7herjMQnKUiB5ExSkUWKwbZ7l4yum3cT0aUUpaqAvKj5DiENaXAqFIPkyMQCiSFcpR8XXxDctm1vUdTk0l31bre_UQyDgFDaLDtX8T2ZPyKjMkb73BF5tYjtq69Iouuq8m08-TS1dUf2rNmY5wftI-SBytTB3x8OE-ST9PTxeRtevFhdjYZX6S2AAGpKIFSjgU1TBZC8aKqKAMr8kKsrMESVSGrJSppOVdmaUsZN4GVAFBKLpGfJM_3vhvf_dhi6HXjgsW6Ni1226ALKVnOy_KfoJCMQk5lBJ_-Ba67rW_jEJoB5RJy4BFSe8j6LgSPK73xrjH-WgPVQ1B6rYc89JCHHoLSN0HpXZQ-Ofhvlw1Wd8JDMhF4dgBMsKZeedNaF-64QjJgfOBe77lfrsbr_36Afjeb31yjQbo3cKHH3a2B8d_jt3Ep9Jf3Mz0FPv94_rnQ5_w3umC7BA</recordid><startdate>200504</startdate><enddate>200504</enddate><creator>Nasreddine, Ziad S.</creator><creator>Phillips, Natalie A.</creator><creator>Bédirian, Valérie</creator><creator>Charbonneau, Simon</creator><creator>Whitehead, Victor</creator><creator>Collin, Isabelle</creator><creator>Cummings, Jeffrey L.</creator><creator>Chertkow, Howard</creator><general>Blackwell Science Inc</general><general>Blackwell</general><general>Wiley Subscription Services, Inc</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QP</scope><scope>7TK</scope><scope>K9.</scope><scope>NAPCQ</scope><scope>7QJ</scope><scope>7X8</scope></search><sort><creationdate>200504</creationdate><title>The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment</title><author>Nasreddine, Ziad S. ; Phillips, Natalie A. ; Bédirian, Valérie ; Charbonneau, Simon ; Whitehead, Victor ; Collin, Isabelle ; Cummings, Jeffrey L. ; Chertkow, Howard</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c6151-591003e60a2765836dd021c5465fcae9e867dbe87c338abc97abc5ed511887be3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Aged</topic><topic>Alzheimer Disease - diagnosis</topic><topic>Alzheimer's</topic><topic>Biological and medical sciences</topic><topic>Canada</topic><topic>Case-Control Studies</topic><topic>Clinical assessment</topic><topic>Cognition & reasoning</topic><topic>Cognition Disorders - diagnosis</topic><topic>cognitive assessment</topic><topic>Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases</topic><topic>Dementia</topic><topic>Elderly people</topic><topic>Female</topic><topic>General aspects</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Medical screening</topic><topic>Mild cognitive disorders</topic><topic>mild cognitive impairment</topic><topic>MoCA</topic><topic>Neurology</topic><topic>Neuropsychological Tests</topic><topic>Older people</topic><topic>Psychometrics</topic><topic>Quebec</topic><topic>Reproducibility of Results</topic><topic>Screening</topic><topic>Sensitivity and Specificity</topic><topic>Validation</topic><topic>Validation studies</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nasreddine, Ziad S.</creatorcontrib><creatorcontrib>Phillips, Natalie A.</creatorcontrib><creatorcontrib>Bédirian, Valérie</creatorcontrib><creatorcontrib>Charbonneau, Simon</creatorcontrib><creatorcontrib>Whitehead, Victor</creatorcontrib><creatorcontrib>Collin, Isabelle</creatorcontrib><creatorcontrib>Cummings, Jeffrey L.</creatorcontrib><creatorcontrib>Chertkow, Howard</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Calcium & Calcified Tissue Abstracts</collection><collection>Neurosciences Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Premium</collection><collection>Applied Social Sciences Index & Abstracts (ASSIA)</collection><collection>MEDLINE - Academic</collection><jtitle>Journal of the American Geriatrics Society</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nasreddine, Ziad S.</au><au>Phillips, Natalie A.</au><au>Bédirian, Valérie</au><au>Charbonneau, Simon</au><au>Whitehead, Victor</au><au>Collin, Isabelle</au><au>Cummings, Jeffrey L.</au><au>Chertkow, Howard</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment</atitle><jtitle>Journal of the American Geriatrics Society</jtitle><addtitle>J Am Geriatr Soc</addtitle><date>2005-04</date><risdate>2005</risdate><volume>53</volume><issue>4</issue><spage>695</spage><epage>699</epage><pages>695-699</pages><issn>0002-8614</issn><eissn>1532-5415</eissn><coden>JAGSAF</coden><abstract>Objectives: To develop a 10‐minute cognitive screening tool (Montreal Cognitive Assessment, MoCA) to assist first‐line physicians in detection of mild cognitive impairment (MCI), a clinical state that often progresses to dementia.
Design: Validation study.
Setting: A community clinic and an academic center.
Participants: Ninety‐four patients meeting MCI clinical criteria supported by psychometric measures, 93 patients with mild Alzheimer's disease (AD) (Mini‐Mental State Examination (MMSE) score≥17), and 90 healthy elderly controls (NC).
Measurements: The MoCA and MMSE were administered to all participants, and sensitivity and specificity of both measures were assessed for detection of MCI and mild AD.
Results: Using a cutoff score 26, the MMSE had a sensitivity of 18% to detect MCI, whereas the MoCA detected 90% of MCI subjects. In the mild AD group, the MMSE had a sensitivity of 78%, whereas the MoCA detected 100%. Specificity was excellent for both MMSE and MoCA (100% and 87%, respectively).
Conclusion: MCI as an entity is evolving and somewhat controversial. The MoCA is a brief cognitive screening tool with high sensitivity and specificity for detecting MCI as currently conceptualized in patients performing in the normal range on the MMSE.</abstract><cop>Oxford, UK</cop><pub>Blackwell Science Inc</pub><pmid>15817019</pmid><doi>10.1111/j.1532-5415.2005.53221.x</doi><tpages>5</tpages></addata></record> |
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subjects | Aged Alzheimer Disease - diagnosis Alzheimer's Biological and medical sciences Canada Case-Control Studies Clinical assessment Cognition & reasoning Cognition Disorders - diagnosis cognitive assessment Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases Dementia Elderly people Female General aspects Humans Male Medical sciences Medical screening Mild cognitive disorders mild cognitive impairment MoCA Neurology Neuropsychological Tests Older people Psychometrics Quebec Reproducibility of Results Screening Sensitivity and Specificity Validation Validation studies |
title | The Montreal Cognitive Assessment, MoCA: A Brief Screening Tool For Mild Cognitive Impairment |
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