High-dose Intravenous Dalteparin Can be Monitored Effectively Using Standard Coagulation Times

The objective of this study was to examine the pharmacokinetics of intravenous dalteparin (Fragmin, Pharmacia-Upjohn, Peapack, NJ) and to assess the accuracy of standard coagulation-based monitoring techniques as an estimate of drug concentration with which to guide dosing. Knowledge of the kinetic...

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Veröffentlicht in:	Clinical and applied thrombosis/hemostasis 2005-04, Vol.11 (2), p.127-138
Hauptverfasser:	Wilson, James M., Gilbert, Jerry, Harlan, Mary, Bracey, Arthur, Allison, Paul, Schooley, Chad, Pinto, Kathleen
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Anticoagulants Blood Coagulation - drug effects Blood Coagulation Tests Calcium - metabolism Dalteparin - administration & dosage Dalteparin - pharmacokinetics Dalteparin - pharmacology Drug dosages Drug Monitoring - methods Factor Xa - metabolism Female Humans Infusions, Intravenous Male Time Factors
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