Identification of NUP98 abnormalities in acute leukemia: JARID1A (12p13) as a new partner gene

Chromosome rearrangements are found in many acute leukemias. As a result, genes at the breakpoints can be disrupted, forming fusion genes. One of the genes involved in several chromosome aberrations in hematological malignancies is NUP98 (11p15). As NUP98 is close to the 11p telomere, small transloc...

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Veröffentlicht in:	Genes chromosomes & cancer 2006-05, Vol.45 (5), p.437-446
Hauptverfasser:	van Zutven, Laura J. C. M., Önen, Emine, Velthuizen, Sandra C. J. M., van Drunen, Ellen, von Bergh, Anne R. M., van den Heuvel-Eibrink, Marry M., Veronese, Angelo, Mecucci, Cristina, Negrini, Massimo, de Greef, Georgine E., Beverloo, H. Berna
Format:	Artikel
Sprache:	eng
Schlagworte:	Acute Disease Adolescent Adult Aged Amino Acid Sequence Base Sequence Child Child, Preschool Chromosomes, Human, Pair 12 DNA Primers Female Humans In Situ Hybridization, Fluorescence Infant Karyotyping Leukemia - genetics Male Middle Aged Molecular Sequence Data Nuclear Pore Complex Proteins - genetics
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