The independent effect of drug resistance on T cell activation in HIV infection

Antiretroviral-treated individuals with drug-resistant HIV experience slower CD4 cell count declines than untreated individuals, independent of degree of viremia. As immune activation independently predicts disease progression, we hypothesized that patients with drug-resistant viremia would have les...

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Veröffentlicht in:	AIDS (London) 2006-03, Vol.20 (5), p.691-699
Hauptverfasser:	HUNT, Peter W, DEEKS, Steven G, MARTIN, Jeffrey N, BANGSBERG, David R, MOSS, Andrew, SINCLAIR, Elizabeth, LIEGLER, Teri, BATES, Michael, TSAO, Gabriel, LAMPIRIS, Harry, HOH, Rebecca
Format:	Artikel
Sprache:	eng
Schlagworte:	ADP-ribosyl Cyclase 1 - analysis Adult AIDS/HIV Anti-Retroviral Agents - therapeutic use Antibiotics. Antiinfectious agents. Antiparasitic agents Antiretroviral Therapy, Highly Active Antiviral agents Biological and medical sciences CD4 Lymphocyte Count CD4-Positive T-Lymphocytes - immunology CD8-Positive T-Lymphocytes - immunology Cross-Sectional Studies Drug Resistance, Viral Female Hepacivirus Hepatitis C - complications Hepatitis C - drug therapy Hepatitis C - immunology HIV Infections - complications HIV Infections - drug therapy HIV Infections - immunology HIV Protease Inhibitors - therapeutic use HIV-1 - genetics HIV-1 - physiology Human immunodeficiency virus Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Lymphocyte Activation - drug effects Male Medical sciences Middle Aged Pharmacology. Drug treatments RNA, Viral - blood Statistics, Nonparametric T-Lymphocytes - immunology Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Viremia
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