TLR Signaling in the Gut in Health and Disease

The human intestine has evolved in the presence of diverse enteric microflora. TLRs convert the recognition of pathogen-associated molecules in the gut into signals for anti-microbial peptide expression, barrier fortification, and proliferation of epithelial cells. Healing of injured intestinal epit...

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Veröffentlicht in:	The Journal of immunology (1950) 2005-04, Vol.174 (8), p.4453-4460
Hauptverfasser:	Abreu, Maria T, Fukata, Masayuki, Arditi, Moshe
Format:	Artikel
Sprache:	eng
Schlagworte:	Adaptor Proteins, Signal Transducing - genetics Adaptor Proteins, Signal Transducing - immunology Bacteria - immunology Bacteria - pathogenicity Enteritis - immunology Humans Immunity, Innate Immunity, Mucosal Inflammatory Bowel Diseases - genetics Inflammatory Bowel Diseases - immunology Intestinal Mucosa - immunology Intestinal Mucosa - microbiology Intracellular Signaling Peptides and Proteins Membrane Glycoproteins - genetics Membrane Glycoproteins - immunology Models, Immunological Nod1 Signaling Adaptor Protein Nod2 Signaling Adaptor Protein Polymorphism, Genetic Receptors, Cell Surface - genetics Receptors, Cell Surface - immunology Signal Transduction Toll-Like Receptors
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