Down-regulation of Histone Deacetylases Stimulates Adipocyte Differentiation

Specific cell type differentiation is driven by programmed regulation of gene expression, which is the result of coordinated modulation of the transcription machinery and chromatin-remodeling factors. We present evidence here that the down-regulation of histone deacetylases is an important process d...

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Veröffentlicht in:	The Journal of biological chemistry 2006-03, Vol.281 (10), p.6608-6615
Hauptverfasser:	Yoo, Eung Jae, Chung, Jun-Jae, Choe, Sung Sik, Kim, Kang Ho, Kim, Jae Bum
Format:	Artikel
Sprache:	eng
Schlagworte:	3T3 Cells Adipocytes - cytology Adipocytes - enzymology Adipogenesis - genetics Adipogenesis - physiology Animals Cell Differentiation - physiology Down-Regulation - physiology Enzyme Inhibitors - pharmacology Histone Deacetylase 1 Histone Deacetylase Inhibitors Histone Deacetylases - biosynthesis Histone Deacetylases - genetics Histone Deacetylases - physiology Histones - metabolism Mice PPAR gamma - metabolism Promoter Regions, Genetic
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