The Effect of a Sertoli Cell-Selective Knockout of the Androgen Receptor on Testicular Gene Expression in Prepubertal Mice

To unravel the molecular mechanisms mediating the effects of androgens on spermatogenesis, testicular gene expression was compared in mice with Sertoli cell-selective androgen receptor knockout (SCARKO) and littermate controls on postnatal d 10. Microarray analysis identified 692 genes with signific...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Molecular endocrinology (Baltimore, Md.) Md.), 2006-02, Vol.20 (2), p.321-334
Hauptverfasser:	Denolet, Evi, De Gendt, Karel, Allemeersch, Joke, Engelen, Kristof, Marchal, Kathleen, Van Hummelen, Paul, Tan, Karen A. L, Sharpe, Richard M, Saunders, Philippa T. K, Swinnen, Johannes V, Verhoeven, Guido
Format:	Artikel
Sprache:	eng
Schlagworte:	Androgens - metabolism Animals Female Gene Expression Profiling Gene Expression Regulation Homeodomain Proteins - genetics Humans Male Mice Oligonucleotide Array Sequence Analysis Receptors, Androgen - genetics Sertoli Cells - metabolism Spermatogenesis - genetics Testis - cytology Testis - growth & development Testis - metabolism Transcription Factors - genetics
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!