Post-systolic shortening during dobutamine stress echocardiography predicts cardiac survival in patients with severe left ventricular dysfunction
BACKGROUNDPatients with severe left ventricular dysfunction and myocardial viability by dobutamine stress echocardiography (DSE) or F18-fluorodeoxyglucose-single-photon emission computed tomography (FDG-SPECT), experience improved survival after coronary revascularization. Pulsed wave-tissue Doppler...
Gespeichert in:
| Veröffentlicht in: | Coronary artery disease 2005-05, Vol.16 (3), p.141-145 |
|---|---|
| Hauptverfasser: | , , , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 145 |
|---|---|
| container_issue | 3 |
| container_start_page | 141 |
| container_title | Coronary artery disease |
| container_volume | 16 |
| creator | Rambaldi, Riccardo Bax, Jeroen J Rizzello, Vittoria Biagini, Elena Valkema, Roelf Roelandt, Jos R.T.C Poldermans, Don |
| description | BACKGROUNDPatients with severe left ventricular dysfunction and myocardial viability by dobutamine stress echocardiography (DSE) or F18-fluorodeoxyglucose-single-photon emission computed tomography (FDG-SPECT), experience improved survival after coronary revascularization. Pulsed wave-tissue Doppler imaging (PW-TDI)-derived ejection phase shortening (EPS) and post-systolic shortening (PSS) velocities may help to quantify DSE. We assessed these variables in a prospective long-term follow-up.
METHODSEighty patients (58 men, mean age 63±9 years) with left ventricular dysfunction (radionuclide ventriculography mean ejection fraction, 34±11%) underwent both DSE and FDG-SPECT for myocardial viability. Viable myocardium was improvement from rest to low dose or worsening of wall motion at peak DSE and normal perfusion, mildly reduced perfusion with FDG uptake or severely reduced or absent perfusion with increased FDG uptake (mismatch) at FDG-SPECT. EPS, PSS velocities and EPS/PSS ratio during DSE were analysed using a six-segment model. Coronary revascularization bypass grafting was performed in 62 patients. All patients completed a long-term (9-year) follow-up for cardiac death.
RESULTSThe segmental prevalence of severe dyssynergy was 77%. On a patient basis myocardial viability was detected by EPS/PSS ratio (31%), FDG-SPECT (34%) and DSE (26%). A significant improvement of Kaplan–Meier survival was predicted in viable compared with nonviable revascularized patients (P |
| doi_str_mv | 10.1097/00019501-200505000-00002 |
| format | Article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_67715846</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>67715846</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3582-930d15cc5471f4e47a759b11f1e75e754c69174ca3b127dba0e5ea08fab4f53d3</originalsourceid><addsrcrecordid>eNp1kcGO1DAMhiMEYmcXXgHlxK3gtMmkPaIVLEgrLQc4R2nqbgOZpsTpjOYxeGPCzAAnFEeW7P-3JX-McQFvBHT6LQCIToGoagBVHkBVPtRP2EZI3VSqbeAp20CnZLXt6vaKXRN9KyaptHrOroRqRQttvWE_P0fKFR0px-AdpymmjLOfH_mwplOK_Zrtzs_IKSck4uim6GwafHxMdpmOfEk4eJeJn6q2TFnT3u9t4H7mi80e59I8-Dxxwj0m5AHHzPelnLxbg018ONK4zi77OL9gz0YbCF9e8g37-uH9l9uP1f3D3afbd_eVa1RbV10Dg1DOKanFKFFqq1XXCzEK1KqEdNtOaOls04taD70FVGihHW0vR9UMzQ17fZ67pPhjRcpm58lhCHbGuJLZal3OJLdF2J6FLkWihKNZkt_ZdDQCzG8c5g8O8xeHOeEo1leXHWu_w-Gf8XL_IpBnwSGGjIm-h_WAyUxoQ57M_zA3vwCmQpoV</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>67715846</pqid></control><display><type>article</type><title>Post-systolic shortening during dobutamine stress echocardiography predicts cardiac survival in patients with severe left ventricular dysfunction</title><source>MEDLINE</source><source>Journals@Ovid Complete</source><creator>Rambaldi, Riccardo ; Bax, Jeroen J ; Rizzello, Vittoria ; Biagini, Elena ; Valkema, Roelf ; Roelandt, Jos R.T.C ; Poldermans, Don</creator><creatorcontrib>Rambaldi, Riccardo ; Bax, Jeroen J ; Rizzello, Vittoria ; Biagini, Elena ; Valkema, Roelf ; Roelandt, Jos R.T.C ; Poldermans, Don</creatorcontrib><description>BACKGROUNDPatients with severe left ventricular dysfunction and myocardial viability by dobutamine stress echocardiography (DSE) or F18-fluorodeoxyglucose-single-photon emission computed tomography (FDG-SPECT), experience improved survival after coronary revascularization. Pulsed wave-tissue Doppler imaging (PW-TDI)-derived ejection phase shortening (EPS) and post-systolic shortening (PSS) velocities may help to quantify DSE. We assessed these variables in a prospective long-term follow-up.
METHODSEighty patients (58 men, mean age 63±9 years) with left ventricular dysfunction (radionuclide ventriculography mean ejection fraction, 34±11%) underwent both DSE and FDG-SPECT for myocardial viability. Viable myocardium was improvement from rest to low dose or worsening of wall motion at peak DSE and normal perfusion, mildly reduced perfusion with FDG uptake or severely reduced or absent perfusion with increased FDG uptake (mismatch) at FDG-SPECT. EPS, PSS velocities and EPS/PSS ratio during DSE were analysed using a six-segment model. Coronary revascularization bypass grafting was performed in 62 patients. All patients completed a long-term (9-year) follow-up for cardiac death.
RESULTSThe segmental prevalence of severe dyssynergy was 77%. On a patient basis myocardial viability was detected by EPS/PSS ratio (31%), FDG-SPECT (34%) and DSE (26%). A significant improvement of Kaplan–Meier survival was predicted in viable compared with nonviable revascularized patients (P<0.01). Both EPS/PSS ratio and FDG-SPECT, compared to DSE alone, tended to allocate more accurately univariate prediction of death-free outcome (odds ratio, 2.5 and 2.7 compared with 2.1).
CONCLUSIONSTDI adds objective variables to DSE, helping to recognize viable myocardium and optimize prediction of death-free outcome in long-term follow-up, with favorable comparison with nuclear techniques.</description><identifier>ISSN: 0954-6928</identifier><identifier>EISSN: 1473-5830</identifier><identifier>DOI: 10.1097/00019501-200505000-00002</identifier><identifier>PMID: 15818082</identifier><language>eng</language><publisher>England: Lippincott Williams & Wilkins, Inc</publisher><subject>Cardiomyopathies - mortality ; Cardiomyopathies - pathology ; Cardiomyopathies - physiopathology ; Cardiomyopathies - therapy ; Coronary Artery Bypass ; Echocardiography, Stress ; Female ; Fluorodeoxyglucose F18 ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Myocardial Ischemia - mortality ; Myocardial Ischemia - pathology ; Myocardial Ischemia - physiopathology ; Myocardial Ischemia - therapy ; Myocardium - pathology ; Netherlands - epidemiology ; Prognosis ; Prospective Studies ; Radiopharmaceuticals ; Stroke Volume - physiology ; Survival Analysis ; Systole - physiology ; Tissue Survival ; Tomography, Emission-Computed, Single-Photon ; Ultrasonography, Doppler, Pulsed ; Ventricular Dysfunction, Left - mortality ; Ventricular Dysfunction, Left - pathology ; Ventricular Dysfunction, Left - physiopathology ; Ventricular Dysfunction, Left - therapy</subject><ispartof>Coronary artery disease, 2005-05, Vol.16 (3), p.141-145</ispartof><rights>2005 Lippincott Williams & Wilkins, Inc.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3582-930d15cc5471f4e47a759b11f1e75e754c69174ca3b127dba0e5ea08fab4f53d3</citedby><cites>FETCH-LOGICAL-c3582-930d15cc5471f4e47a759b11f1e75e754c69174ca3b127dba0e5ea08fab4f53d3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27903,27904</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15818082$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Rambaldi, Riccardo</creatorcontrib><creatorcontrib>Bax, Jeroen J</creatorcontrib><creatorcontrib>Rizzello, Vittoria</creatorcontrib><creatorcontrib>Biagini, Elena</creatorcontrib><creatorcontrib>Valkema, Roelf</creatorcontrib><creatorcontrib>Roelandt, Jos R.T.C</creatorcontrib><creatorcontrib>Poldermans, Don</creatorcontrib><title>Post-systolic shortening during dobutamine stress echocardiography predicts cardiac survival in patients with severe left ventricular dysfunction</title><title>Coronary artery disease</title><addtitle>Coron Artery Dis</addtitle><description>BACKGROUNDPatients with severe left ventricular dysfunction and myocardial viability by dobutamine stress echocardiography (DSE) or F18-fluorodeoxyglucose-single-photon emission computed tomography (FDG-SPECT), experience improved survival after coronary revascularization. Pulsed wave-tissue Doppler imaging (PW-TDI)-derived ejection phase shortening (EPS) and post-systolic shortening (PSS) velocities may help to quantify DSE. We assessed these variables in a prospective long-term follow-up.
METHODSEighty patients (58 men, mean age 63±9 years) with left ventricular dysfunction (radionuclide ventriculography mean ejection fraction, 34±11%) underwent both DSE and FDG-SPECT for myocardial viability. Viable myocardium was improvement from rest to low dose or worsening of wall motion at peak DSE and normal perfusion, mildly reduced perfusion with FDG uptake or severely reduced or absent perfusion with increased FDG uptake (mismatch) at FDG-SPECT. EPS, PSS velocities and EPS/PSS ratio during DSE were analysed using a six-segment model. Coronary revascularization bypass grafting was performed in 62 patients. All patients completed a long-term (9-year) follow-up for cardiac death.
RESULTSThe segmental prevalence of severe dyssynergy was 77%. On a patient basis myocardial viability was detected by EPS/PSS ratio (31%), FDG-SPECT (34%) and DSE (26%). A significant improvement of Kaplan–Meier survival was predicted in viable compared with nonviable revascularized patients (P<0.01). Both EPS/PSS ratio and FDG-SPECT, compared to DSE alone, tended to allocate more accurately univariate prediction of death-free outcome (odds ratio, 2.5 and 2.7 compared with 2.1).
CONCLUSIONSTDI adds objective variables to DSE, helping to recognize viable myocardium and optimize prediction of death-free outcome in long-term follow-up, with favorable comparison with nuclear techniques.</description><subject>Cardiomyopathies - mortality</subject><subject>Cardiomyopathies - pathology</subject><subject>Cardiomyopathies - physiopathology</subject><subject>Cardiomyopathies - therapy</subject><subject>Coronary Artery Bypass</subject><subject>Echocardiography, Stress</subject><subject>Female</subject><subject>Fluorodeoxyglucose F18</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myocardial Ischemia - mortality</subject><subject>Myocardial Ischemia - pathology</subject><subject>Myocardial Ischemia - physiopathology</subject><subject>Myocardial Ischemia - therapy</subject><subject>Myocardium - pathology</subject><subject>Netherlands - epidemiology</subject><subject>Prognosis</subject><subject>Prospective Studies</subject><subject>Radiopharmaceuticals</subject><subject>Stroke Volume - physiology</subject><subject>Survival Analysis</subject><subject>Systole - physiology</subject><subject>Tissue Survival</subject><subject>Tomography, Emission-Computed, Single-Photon</subject><subject>Ultrasonography, Doppler, Pulsed</subject><subject>Ventricular Dysfunction, Left - mortality</subject><subject>Ventricular Dysfunction, Left - pathology</subject><subject>Ventricular Dysfunction, Left - physiopathology</subject><subject>Ventricular Dysfunction, Left - therapy</subject><issn>0954-6928</issn><issn>1473-5830</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kcGO1DAMhiMEYmcXXgHlxK3gtMmkPaIVLEgrLQc4R2nqbgOZpsTpjOYxeGPCzAAnFEeW7P-3JX-McQFvBHT6LQCIToGoagBVHkBVPtRP2EZI3VSqbeAp20CnZLXt6vaKXRN9KyaptHrOroRqRQttvWE_P0fKFR0px-AdpymmjLOfH_mwplOK_Zrtzs_IKSck4uim6GwafHxMdpmOfEk4eJeJn6q2TFnT3u9t4H7mi80e59I8-Dxxwj0m5AHHzPelnLxbg018ONK4zi77OL9gz0YbCF9e8g37-uH9l9uP1f3D3afbd_eVa1RbV10Dg1DOKanFKFFqq1XXCzEK1KqEdNtOaOls04taD70FVGihHW0vR9UMzQ17fZ67pPhjRcpm58lhCHbGuJLZal3OJLdF2J6FLkWihKNZkt_ZdDQCzG8c5g8O8xeHOeEo1leXHWu_w-Gf8XL_IpBnwSGGjIm-h_WAyUxoQ57M_zA3vwCmQpoV</recordid><startdate>200505</startdate><enddate>200505</enddate><creator>Rambaldi, Riccardo</creator><creator>Bax, Jeroen J</creator><creator>Rizzello, Vittoria</creator><creator>Biagini, Elena</creator><creator>Valkema, Roelf</creator><creator>Roelandt, Jos R.T.C</creator><creator>Poldermans, Don</creator><general>Lippincott Williams & Wilkins, Inc</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200505</creationdate><title>Post-systolic shortening during dobutamine stress echocardiography predicts cardiac survival in patients with severe left ventricular dysfunction</title><author>Rambaldi, Riccardo ; Bax, Jeroen J ; Rizzello, Vittoria ; Biagini, Elena ; Valkema, Roelf ; Roelandt, Jos R.T.C ; Poldermans, Don</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3582-930d15cc5471f4e47a759b11f1e75e754c69174ca3b127dba0e5ea08fab4f53d3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Cardiomyopathies - mortality</topic><topic>Cardiomyopathies - pathology</topic><topic>Cardiomyopathies - physiopathology</topic><topic>Cardiomyopathies - therapy</topic><topic>Coronary Artery Bypass</topic><topic>Echocardiography, Stress</topic><topic>Female</topic><topic>Fluorodeoxyglucose F18</topic><topic>Follow-Up Studies</topic><topic>Humans</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Myocardial Ischemia - mortality</topic><topic>Myocardial Ischemia - pathology</topic><topic>Myocardial Ischemia - physiopathology</topic><topic>Myocardial Ischemia - therapy</topic><topic>Myocardium - pathology</topic><topic>Netherlands - epidemiology</topic><topic>Prognosis</topic><topic>Prospective Studies</topic><topic>Radiopharmaceuticals</topic><topic>Stroke Volume - physiology</topic><topic>Survival Analysis</topic><topic>Systole - physiology</topic><topic>Tissue Survival</topic><topic>Tomography, Emission-Computed, Single-Photon</topic><topic>Ultrasonography, Doppler, Pulsed</topic><topic>Ventricular Dysfunction, Left - mortality</topic><topic>Ventricular Dysfunction, Left - pathology</topic><topic>Ventricular Dysfunction, Left - physiopathology</topic><topic>Ventricular Dysfunction, Left - therapy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Rambaldi, Riccardo</creatorcontrib><creatorcontrib>Bax, Jeroen J</creatorcontrib><creatorcontrib>Rizzello, Vittoria</creatorcontrib><creatorcontrib>Biagini, Elena</creatorcontrib><creatorcontrib>Valkema, Roelf</creatorcontrib><creatorcontrib>Roelandt, Jos R.T.C</creatorcontrib><creatorcontrib>Poldermans, Don</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Coronary artery disease</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Rambaldi, Riccardo</au><au>Bax, Jeroen J</au><au>Rizzello, Vittoria</au><au>Biagini, Elena</au><au>Valkema, Roelf</au><au>Roelandt, Jos R.T.C</au><au>Poldermans, Don</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Post-systolic shortening during dobutamine stress echocardiography predicts cardiac survival in patients with severe left ventricular dysfunction</atitle><jtitle>Coronary artery disease</jtitle><addtitle>Coron Artery Dis</addtitle><date>2005-05</date><risdate>2005</risdate><volume>16</volume><issue>3</issue><spage>141</spage><epage>145</epage><pages>141-145</pages><issn>0954-6928</issn><eissn>1473-5830</eissn><abstract>BACKGROUNDPatients with severe left ventricular dysfunction and myocardial viability by dobutamine stress echocardiography (DSE) or F18-fluorodeoxyglucose-single-photon emission computed tomography (FDG-SPECT), experience improved survival after coronary revascularization. Pulsed wave-tissue Doppler imaging (PW-TDI)-derived ejection phase shortening (EPS) and post-systolic shortening (PSS) velocities may help to quantify DSE. We assessed these variables in a prospective long-term follow-up.
METHODSEighty patients (58 men, mean age 63±9 years) with left ventricular dysfunction (radionuclide ventriculography mean ejection fraction, 34±11%) underwent both DSE and FDG-SPECT for myocardial viability. Viable myocardium was improvement from rest to low dose or worsening of wall motion at peak DSE and normal perfusion, mildly reduced perfusion with FDG uptake or severely reduced or absent perfusion with increased FDG uptake (mismatch) at FDG-SPECT. EPS, PSS velocities and EPS/PSS ratio during DSE were analysed using a six-segment model. Coronary revascularization bypass grafting was performed in 62 patients. All patients completed a long-term (9-year) follow-up for cardiac death.
RESULTSThe segmental prevalence of severe dyssynergy was 77%. On a patient basis myocardial viability was detected by EPS/PSS ratio (31%), FDG-SPECT (34%) and DSE (26%). A significant improvement of Kaplan–Meier survival was predicted in viable compared with nonviable revascularized patients (P<0.01). Both EPS/PSS ratio and FDG-SPECT, compared to DSE alone, tended to allocate more accurately univariate prediction of death-free outcome (odds ratio, 2.5 and 2.7 compared with 2.1).
CONCLUSIONSTDI adds objective variables to DSE, helping to recognize viable myocardium and optimize prediction of death-free outcome in long-term follow-up, with favorable comparison with nuclear techniques.</abstract><cop>England</cop><pub>Lippincott Williams & Wilkins, Inc</pub><pmid>15818082</pmid><doi>10.1097/00019501-200505000-00002</doi><tpages>5</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0954-6928 |
| ispartof | Coronary artery disease, 2005-05, Vol.16 (3), p.141-145 |
| issn | 0954-6928 1473-5830 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_67715846 |
| source | MEDLINE; Journals@Ovid Complete |
| subjects | Cardiomyopathies - mortality Cardiomyopathies - pathology Cardiomyopathies - physiopathology Cardiomyopathies - therapy Coronary Artery Bypass Echocardiography, Stress Female Fluorodeoxyglucose F18 Follow-Up Studies Humans Male Middle Aged Myocardial Ischemia - mortality Myocardial Ischemia - pathology Myocardial Ischemia - physiopathology Myocardial Ischemia - therapy Myocardium - pathology Netherlands - epidemiology Prognosis Prospective Studies Radiopharmaceuticals Stroke Volume - physiology Survival Analysis Systole - physiology Tissue Survival Tomography, Emission-Computed, Single-Photon Ultrasonography, Doppler, Pulsed Ventricular Dysfunction, Left - mortality Ventricular Dysfunction, Left - pathology Ventricular Dysfunction, Left - physiopathology Ventricular Dysfunction, Left - therapy |
| title | Post-systolic shortening during dobutamine stress echocardiography predicts cardiac survival in patients with severe left ventricular dysfunction |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-28T04%3A31%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Post-systolic%20shortening%20during%20dobutamine%20stress%20echocardiography%20predicts%20cardiac%20survival%20in%20patients%20with%20severe%20left%20ventricular%20dysfunction&rft.jtitle=Coronary%20artery%20disease&rft.au=Rambaldi,%20Riccardo&rft.date=2005-05&rft.volume=16&rft.issue=3&rft.spage=141&rft.epage=145&rft.pages=141-145&rft.issn=0954-6928&rft.eissn=1473-5830&rft_id=info:doi/10.1097/00019501-200505000-00002&rft_dat=%3Cproquest_cross%3E67715846%3C/proquest_cross%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=67715846&rft_id=info:pmid/15818082&rfr_iscdi=true |