Activation of either ERK1/2 or ERK5 MAP kinase pathways can lead to disruption of the actin cytoskeleton

Oncogenic transformation often leads to the disruption of the actin cytoskeleton. Activation of the classical Ras-Raf-MEK1/2-ERK1/2 signalling cascade has been implicated in the effects of oncogenes such as Ras and Src on the cytoskeleton. Many of the studies of the effects of oncogenes on the cytos...

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Veröffentlicht in:Journal of cell science 2005-04, Vol.118 (8), p.1663-1671
Hauptverfasser: Barros, Joana Castro, Marshall, Christopher J
Format: Artikel
Sprache:eng
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