Lessons learned from randomised clinical trials in adult low grade glioma
“Lesson” is a Middle English word that has been defined as “a passage from sacred writings read in a service of worship” as well as “something learned by study or experience”. The term is quite appropriate in assessment of what has been learned from randomised trials in adult low-grade gliomas, sinc...
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| Veröffentlicht in: | The lancet oncology 2005-04, Vol.6 (4), p.240-244 |
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| container_title | The lancet oncology |
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| creator | Papagikos, Michael A Shaw, Edward G Stieber, Volker W |
| description | “Lesson” is a Middle English word that has been defined as “a passage from sacred writings read in a service of worship” as well as “something learned by study or experience”. The term is quite appropriate in assessment of what has been learned from randomised trials in adult low-grade gliomas, since the treatment of these tumours has traditionally been guided as much by belief as by fact. Therefore, when assessing these trials we can apply the principles of hermeneutics. Thus, the first meaning of “lesson” given here can be described as literal, whereas the second may be seen as figurative. Since hermeneutics may also refer to an in-depth analysis of a particular text, the investigators will present their interpretation of data from randomised trials. The goal is to show that the lessons learned are not necessarily literal or dogmatic but can be much more allegorical in nature. |
| doi_str_mv | 10.1016/S1470-2045(05)70095-4 |
| format | Article |
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Shaw, Edward G ; Stieber, Volker W</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c390t-d79c594640fe38a8b3ea195c4f35a25436b94ac2e2434efb8875880a7e62ad543</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2005</creationdate><topic>Adult</topic><topic>Biopsy</topic><topic>Brain cancer</topic><topic>Brain Neoplasms - radiotherapy</topic><topic>Cancer therapies</topic><topic>Chemotherapy, Adjuvant</topic><topic>Glioma - radiotherapy</topic><topic>Histology</topic><topic>Humans</topic><topic>Medical prognosis</topic><topic>Oncology</topic><topic>Prognosis</topic><topic>Quality of Life</topic><topic>Radiation therapy</topic><topic>Radiotherapy Dosage</topic><topic>Randomized Controlled Trials as Topic</topic><topic>Surgery</topic><topic>Treatment Outcome</topic><topic>Tumors</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Papagikos, Michael A</creatorcontrib><creatorcontrib>Shaw, Edward G</creatorcontrib><creatorcontrib>Stieber, Volker W</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>Lancet Titles</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>The lancet oncology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Papagikos, Michael A</au><au>Shaw, Edward G</au><au>Stieber, Volker W</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lessons learned from randomised clinical trials in adult low grade glioma</atitle><jtitle>The lancet oncology</jtitle><addtitle>Lancet Oncol</addtitle><date>2005-04-01</date><risdate>2005</risdate><volume>6</volume><issue>4</issue><spage>240</spage><epage>244</epage><pages>240-244</pages><issn>1470-2045</issn><eissn>1474-5488</eissn><coden>LANCAO</coden><abstract>“Lesson” is a Middle English word that has been defined as “a passage from sacred writings read in a service of worship” as well as “something learned by study or experience”. The term is quite appropriate in assessment of what has been learned from randomised trials in adult low-grade gliomas, since the treatment of these tumours has traditionally been guided as much by belief as by fact. Therefore, when assessing these trials we can apply the principles of hermeneutics. Thus, the first meaning of “lesson” given here can be described as literal, whereas the second may be seen as figurative. Since hermeneutics may also refer to an in-depth analysis of a particular text, the investigators will present their interpretation of data from randomised trials. The goal is to show that the lessons learned are not necessarily literal or dogmatic but can be much more allegorical in nature.</abstract><cop>England</cop><pub>Elsevier Ltd</pub><pmid>15811619</pmid><doi>10.1016/S1470-2045(05)70095-4</doi><tpages>5</tpages></addata></record> |
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| subjects | Adult Biopsy Brain cancer Brain Neoplasms - radiotherapy Cancer therapies Chemotherapy, Adjuvant Glioma - radiotherapy Histology Humans Medical prognosis Oncology Prognosis Quality of Life Radiation therapy Radiotherapy Dosage Randomized Controlled Trials as Topic Surgery Treatment Outcome Tumors |
| title | Lessons learned from randomised clinical trials in adult low grade glioma |
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