Monitoring recovery after laser surgery of the breast with optical tomography: a case study
Results are presented of a study to monitor the changes in the optical properties of breast tissue over a 12-month period after interstitial laser photocoagulation treatment of a fibroadenoma. The study involved generating cross-sectional images of the breast with a multichannel time-resolved imagin...
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Veröffentlicht in: | Applied Optics 2005-04, Vol.44 (10), p.1898-1904 |
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container_end_page | 1904 |
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container_issue | 10 |
container_start_page | 1898 |
container_title | Applied Optics |
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creator | Hebden, Jeremy C Yates, Tara D Gibson, Adam Everdell, Nicholas Arridge, Simon R Chicken, Dennis W Douek, Michael Keshtgar, Mohammed R S |
description | Results are presented of a study to monitor the changes in the optical properties of breast tissue over a 12-month period after interstitial laser photocoagulation treatment of a fibroadenoma. The study involved generating cross-sectional images of the breast with a multichannel time-resolved imaging system and a nonlinear image reconstruction algorithm. Images of the internal absorbing and scattering properties revealed the expected initial inflammatory response, followed by the development of low-scattering cysts consistent with corresponding ultrasound examinations. Although results indicate that purely qualitative images can potentially provide clinically valuable data, means of enhancing diagnostic information by overcoming present limitations of the approach are discussed. |
doi_str_mv | 10.1364/AO.44.001898 |
format | Article |
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Although results indicate that purely qualitative images can potentially provide clinically valuable data, means of enhancing diagnostic information by overcoming present limitations of the approach are discussed.</description><identifier>ISSN: 1559-128X</identifier><identifier>ISSN: 0003-6935</identifier><identifier>EISSN: 1539-4522</identifier><identifier>DOI: 10.1364/AO.44.001898</identifier><identifier>PMID: 15813526</identifier><language>eng</language><publisher>United States</publisher><subject>Adult ; Algorithms ; Breast Neoplasms - diagnostic imaging ; Breast Neoplasms - pathology ; Breast Neoplasms - surgery ; Female ; Fibroadenoma - diagnostic imaging ; Fibroadenoma - pathology ; Fibroadenoma - surgery ; Follow-Up Studies ; Humans ; Image Interpretation, Computer-Assisted - methods ; Laser Therapy - methods ; Prognosis ; Reproducibility of Results ; Sensitivity and Specificity ; Tomography, Optical - methods ; Treatment Outcome ; Ultrasonography</subject><ispartof>Applied Optics, 2005-04, Vol.44 (10), p.1898-1904</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c289t-d88615b7615a827747b31ef86b2242b5ab5d58f59b143ea1f43e22be78b721163</citedby><cites>FETCH-LOGICAL-c289t-d88615b7615a827747b31ef86b2242b5ab5d58f59b143ea1f43e22be78b721163</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,27901,27902</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15813526$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Hebden, Jeremy C</creatorcontrib><creatorcontrib>Yates, Tara D</creatorcontrib><creatorcontrib>Gibson, Adam</creatorcontrib><creatorcontrib>Everdell, Nicholas</creatorcontrib><creatorcontrib>Arridge, Simon R</creatorcontrib><creatorcontrib>Chicken, Dennis W</creatorcontrib><creatorcontrib>Douek, Michael</creatorcontrib><creatorcontrib>Keshtgar, Mohammed R S</creatorcontrib><title>Monitoring recovery after laser surgery of the breast with optical tomography: a case study</title><title>Applied Optics</title><addtitle>Appl Opt</addtitle><description>Results are presented of a study to monitor the changes in the optical properties of breast tissue over a 12-month period after interstitial laser photocoagulation treatment of a fibroadenoma. The study involved generating cross-sectional images of the breast with a multichannel time-resolved imaging system and a nonlinear image reconstruction algorithm. Images of the internal absorbing and scattering properties revealed the expected initial inflammatory response, followed by the development of low-scattering cysts consistent with corresponding ultrasound examinations. Although results indicate that purely qualitative images can potentially provide clinically valuable data, means of enhancing diagnostic information by overcoming present limitations of the approach are discussed.</description><subject>Adult</subject><subject>Algorithms</subject><subject>Breast Neoplasms - diagnostic imaging</subject><subject>Breast Neoplasms - pathology</subject><subject>Breast Neoplasms - surgery</subject><subject>Female</subject><subject>Fibroadenoma - diagnostic imaging</subject><subject>Fibroadenoma - pathology</subject><subject>Fibroadenoma - surgery</subject><subject>Follow-Up Studies</subject><subject>Humans</subject><subject>Image Interpretation, Computer-Assisted - methods</subject><subject>Laser Therapy - methods</subject><subject>Prognosis</subject><subject>Reproducibility of Results</subject><subject>Sensitivity and Specificity</subject><subject>Tomography, Optical - methods</subject><subject>Treatment Outcome</subject><subject>Ultrasonography</subject><issn>1559-128X</issn><issn>0003-6935</issn><issn>1539-4522</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2005</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNpFkM1LwzAYh4MoTqc3z5KTJzvz2aTexvALJrsoCB5C0iZbpV1qkir97-3YwMvvfXl53t_hAeAKoxmmObubr2aMzRDCspBH4AxzWmSME3K823mRYSI_JuA8xi-EKGeFOAUTzCWmnORn4PPVb-vkQ71dw2BL_2PDALVLNsBGxzFjH9a7m3cwbSw0weqY4G-dNtB3qS51A5Nv_TrobjPcQw3L8Q3G1FfDBThxuon28jCn4P3x4W3xnC1XTy-L-TIriSxSVkmZY27EGFoSIZgwFFsnc0MII4ZrwysuHS8MZtRq7MYkxFghjSAY53QKbva9XfDfvY1JtXUsbdPorfV9VLkQSHJERvB2D5bBxxisU12oWx0GhZHayVTzlWJM7WWO-PWhtzetrf7hgz36B44vb3Q</recordid><startdate>20050401</startdate><enddate>20050401</enddate><creator>Hebden, Jeremy C</creator><creator>Yates, Tara D</creator><creator>Gibson, Adam</creator><creator>Everdell, Nicholas</creator><creator>Arridge, Simon R</creator><creator>Chicken, Dennis W</creator><creator>Douek, Michael</creator><creator>Keshtgar, Mohammed R S</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>20050401</creationdate><title>Monitoring recovery after laser surgery of the breast with optical tomography: a case study</title><author>Hebden, Jeremy C ; 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source | MEDLINE; Alma/SFX Local Collection; Optica Publishing Group Journals |
subjects | Adult Algorithms Breast Neoplasms - diagnostic imaging Breast Neoplasms - pathology Breast Neoplasms - surgery Female Fibroadenoma - diagnostic imaging Fibroadenoma - pathology Fibroadenoma - surgery Follow-Up Studies Humans Image Interpretation, Computer-Assisted - methods Laser Therapy - methods Prognosis Reproducibility of Results Sensitivity and Specificity Tomography, Optical - methods Treatment Outcome Ultrasonography |
title | Monitoring recovery after laser surgery of the breast with optical tomography: a case study |
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