Monitoring recovery after laser surgery of the breast with optical tomography: a case study

Results are presented of a study to monitor the changes in the optical properties of breast tissue over a 12-month period after interstitial laser photocoagulation treatment of a fibroadenoma. The study involved generating cross-sectional images of the breast with a multichannel time-resolved imagin...

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Veröffentlicht in:Applied Optics 2005-04, Vol.44 (10), p.1898-1904
Hauptverfasser: Hebden, Jeremy C, Yates, Tara D, Gibson, Adam, Everdell, Nicholas, Arridge, Simon R, Chicken, Dennis W, Douek, Michael, Keshtgar, Mohammed R S
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container_end_page 1904
container_issue 10
container_start_page 1898
container_title Applied Optics
container_volume 44
creator Hebden, Jeremy C
Yates, Tara D
Gibson, Adam
Everdell, Nicholas
Arridge, Simon R
Chicken, Dennis W
Douek, Michael
Keshtgar, Mohammed R S
description Results are presented of a study to monitor the changes in the optical properties of breast tissue over a 12-month period after interstitial laser photocoagulation treatment of a fibroadenoma. The study involved generating cross-sectional images of the breast with a multichannel time-resolved imaging system and a nonlinear image reconstruction algorithm. Images of the internal absorbing and scattering properties revealed the expected initial inflammatory response, followed by the development of low-scattering cysts consistent with corresponding ultrasound examinations. Although results indicate that purely qualitative images can potentially provide clinically valuable data, means of enhancing diagnostic information by overcoming present limitations of the approach are discussed.
doi_str_mv 10.1364/AO.44.001898
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source MEDLINE; Alma/SFX Local Collection; Optica Publishing Group Journals
subjects Adult
Algorithms
Breast Neoplasms - diagnostic imaging
Breast Neoplasms - pathology
Breast Neoplasms - surgery
Female
Fibroadenoma - diagnostic imaging
Fibroadenoma - pathology
Fibroadenoma - surgery
Follow-Up Studies
Humans
Image Interpretation, Computer-Assisted - methods
Laser Therapy - methods
Prognosis
Reproducibility of Results
Sensitivity and Specificity
Tomography, Optical - methods
Treatment Outcome
Ultrasonography
title Monitoring recovery after laser surgery of the breast with optical tomography: a case study
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