Cloning and characterization of two genes encoding rainbow trout homologues of the IFITM protein family

To identify genes connected with leucocyte function in rainbow trout a cDNA library derived from head kidney leucocytes exposed to phytohemagglutinin (PHA) was screened. A clone with homology to the previously described human interferon-inducible transmembrane proteins (IFITM) was isolated. This clo...

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Veröffentlicht in:	Veterinary Immunology and Immunopathology 2006-04, Vol.110 (3), p.357-362
Hauptverfasser:	Johnson, Mark C., Sangrador-Vegas, Amaia, Smith, Terry J., Cairns, Michael T.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence amino acid sequences animal organs animal proteins Animals Base Sequence binding sites Cloning, Molecular complementary DNA disease models DNA libraries exons fish Fish Proteins - chemistry Fish Proteins - genetics gene expression Gene Expression Profiling head kidneys in vitro studies Interferon-inducible interferon-inducible transmembrane proteins interferons Interferons - pharmacology leukocytes macrophages Membrane Proteins - chemistry Membrane Proteins - genetics Molecular Sequence Data Oncorhynchus mykiss Oncorhynchus mykiss - genetics promoter regions Promoters RNA, Messenger - metabolism Teleost transcription (genetics) transcription factors Transmembrane transmembrane proteins viral diseases of animals and humans
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