Progression of diabetic retinopathy during improved metabolic control may be treated with reduced insulin dosage and/or somatostatin analogue administration – a case report

It is well known that intensified insulin treatment of poorly controlled type 1 diabetic patients may worsen an existing diabetic retinopathy (DR). This observation has been explained by an insulin-induced stimulation of the GH/IGF-I axis. Here, we report on three cases, where the progression of DR...

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Veröffentlicht in:	Growth hormone & IGF research 2005-04, Vol.15 (2), p.130-135
Hauptverfasser:	Chantelau, E., Frystyk, J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Albuminuria Creatinine - blood Cystatin C Cystatins - blood Diabetes complications Diabetes Mellitus, Type 1 - complications Diabetic Retinopathy - complications Diabetic Retinopathy - drug therapy Diabetic Retinopathy - metabolism Drug Therapy, Combination Early worsening of retinopathy Female Glycated Hemoglobin A - analysis Hemoglobin A - metabolism Human Growth Hormone - physiology Humans Insulin - administration & dosage Insulin - therapeutic use Insulin-Like Growth Factor Binding Protein 3 - blood Insulin-Like Growth Factor I - metabolism Intensive insulin therapy Male Metabolic control Neovascularization, Pathologic - drug therapy Octreotide - therapeutic use Proliferative retinopathy Syndrome
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