The conundrum of CD40 function: host protection or disease promotion?

T cells regulate the immune responses to pathogens and autoantigens. The immune responses are tolerizing or anti-inflammatory against autoantigens but are inflammatory against pathogens and allografts. Such contradictory immune responses have been attributed to two counteracting effector cell types...

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Veröffentlicht in:	Trends in parasitology 2006-03, Vol.22 (3), p.117-122
Hauptverfasser:	Mathur, Ram K., Awasthi, Amit, Saha, Bhaskar
Format:	Artikel
Sprache:	eng
Schlagworte:	Animal and plant ecology Animal, plant and microbial ecology Animals Autoecology Biological and medical sciences CD40 Antigens - immunology CD40 Antigens - physiology CD40 Ligand Fundamental and applied biological sciences. Psychology Humans Lymphocyte Activation Parasitic Diseases - immunology Protozoa. Invertebrata T-Lymphocytes - immunology
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