Interleukin-10 −1082 G/A polymorphism and risk of death or bronchopulmonary dysplasia in ventilated very low birth weight infants

IL‐10 is an anti‐inflammatory cytokine that may have a protective role in acute lung injury. IL‐10 expression is affected by a single‐nucleotide polymorphism (SNP) located at position −1082 (G to A). The A allele is associated with lower IL‐10 production. Low IL‐10 production has been linked to the...

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Veröffentlicht in:	Pediatric pulmonology 2005-05, Vol.39 (5), p.426-432
Hauptverfasser:	Yanamandra, Krishna, Boggs, Peter, Loggins, John, Baier, R. John
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenine Alleles Biological and medical sciences bronchopulmonary dysplasia Bronchopulmonary Dysplasia - genetics Case-Control Studies Cause of Death Diseases of mother, fetus and pregnancy Ethnic Groups - genetics Female Gene Frequency gene polymorphism Genotype Guanine Gynecology. Andrology. Obstetrics Heterozygote Homozygote Humans Infant, Newborn Infant, Premature Infant, Very Low Birth Weight interleukin-10 Interleukin-10 - genetics Male Medical sciences Pneumology Polymorphism, Single Nucleotide - genetics Pregnancy. Fetus. Placenta prematurity Prospective Studies Respiration, Artificial Respiratory system : syndromes and miscellaneous diseases Risk Factors Sex Factors Trachea - microbiology
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