Decrease of type IV collagen and TIMP-1 serum levels after splenectomy in patients with schistosomiasis mansoni

The role of the spleen in the process of liver fibrosis in schistosomiasis still needs clarification. The aim of this study was to assess the effect of splenectomy on serum levels of two markers of fibrosis, type IV collagen and TIMP-1, in patients with schistosomiasis mansoni. Twenty-four patients...

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Veröffentlicht in:	Acta tropica 2006-03, Vol.97 (3), p.301-308
Hauptverfasser:	Wyszomirska, Rozangela M.A.F., Lacet, Celina da Costa, Tenório, Laércio Ribeiro, Nishimura, Nancy F., Mesquita, Maria Aparecida, Neto, João Batista, Oliveira, Francisco, Balwani, Maria do Carmo Lins Vasconcelos, Almeida, Jazon Romilson Souza, Soares, Elza Cotrim
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Biomarkers Collagen Type IV - blood Female Humans Liver Cirrhosis - blood Liver fibrosis Male Middle Aged Schistosomiasis mansoni Schistosomiasis mansoni - blood Spleen Splenectomy TIMP-1 Tissue Inhibitor of Metalloproteinase-1 - blood Type IV collagen
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