Genome-wide loss of heterozygosity analysis of WT1-wild-type and WT1-mutant Wilms tumors

Wilms tumor (WT) is genetically heterogeneous, and the one known WT gene, WT1 at 11p13, is altered in only a subset of WTs. Previous loss of heterozygosity (LOH) analyses have revealed the existence of additional putative WT genes at 11p15, 16q, and 1p, but these analyses examined only one or a hand...

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Veröffentlicht in:	Genes chromosomes & cancer 2005-06, Vol.43 (2), p.172-180
Hauptverfasser:	Ruteshouser, E. Cristy, Hendrickson, Brett W., Colella, Stefano, Krahe, Ralf, Pinto, Lancelot, Huff, Vicki
Format:	Artikel
Sprache:	eng
Schlagworte:	Child Child, Preschool Genes, Wilms Tumor Genome Humans Infant Loss of Heterozygosity Microsatellite Repeats - genetics Mutation Wilms Tumor - genetics
Online-Zugang:	Volltext
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