Rabies virus receptors

There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind rabies virus and/or facilitate rabies virus entry into cells. Other components of the cell membran...

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Veröffentlicht in:Journal of neurovirology 2005-02, Vol.11 (1), p.82-87
1. Verfasser: Lafon, Monique
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description There is convincing in vitro evidence that the muscular form of the nicotinic acetylcholine receptor (nAChR), the neuronal cell adhesion molecule (NCAM), and the p75 neurotrophin receptor (p75NTR) bind rabies virus and/or facilitate rabies virus entry into cells. Other components of the cell membrane, such as gangliosides, may also participate in the entry of rabies virus. However, little is known of the role of these molecules in vivo. This review proposes a speculative model that accounts for the role of these different molecules in entry and trafficking of rabies virus into the nervous system.
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Other components of the cell membrane, such as gangliosides, may also participate in the entry of rabies virus. However, little is known of the role of these molecules in vivo. This review proposes a speculative model that accounts for the role of these different molecules in entry and trafficking of rabies virus into the nervous system.</description><identifier>ISSN: 1355-0284</identifier><identifier>EISSN: 1538-2443</identifier><identifier>DOI: 10.1080/13550280590900427</identifier><identifier>PMID: 15804965</identifier><language>eng</language><publisher>London: Informa UK Ltd</publisher><subject>Animals ; Biological and medical sciences ; Human viral diseases ; Humans ; Infectious diseases ; Medical sciences ; Neural Cell Adhesion Molecules - metabolism ; Neurons - virology ; Rabies virus ; Rabies virus - pathogenicity ; Receptor, Nerve Growth Factor ; Receptors, Nerve Growth Factor - metabolism ; Receptors, Nicotinic - metabolism ; Receptors, Virus ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. 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Other components of the cell membrane, such as gangliosides, may also participate in the entry of rabies virus. However, little is known of the role of these molecules in vivo. 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subjects Animals
Biological and medical sciences
Human viral diseases
Humans
Infectious diseases
Medical sciences
Neural Cell Adhesion Molecules - metabolism
Neurons - virology
Rabies virus
Rabies virus - pathogenicity
Receptor, Nerve Growth Factor
Receptors, Nerve Growth Factor - metabolism
Receptors, Nicotinic - metabolism
Receptors, Virus
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Viral diseases of the nervous system
Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye
title Rabies virus receptors
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