Mathematical modeling of calcium homeostasis in yeast cells

In this study, based on currently available experimental observations on protein level, we constructed a mathematical model to describe calcium homeostasis in normally growing yeast cells ( Saccharomyces cerevisiae). Simulation results show that tightly controlled low cytosolic calcium ion level can...

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Veröffentlicht in:	Cell calcium (Edinburgh) 2006-04, Vol.39 (4), p.337-348
Hauptverfasser:	Cui, Jiangjun, Kaandorp, Jaap A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Calcineurin - metabolism Calcium - metabolism Calcium - physiology Calcium Channels - physiology Calcium homeostasis Calcium-Transporting ATPases - genetics Calcium-Transporting ATPases - physiology Calmodulin - metabolism Computer Simulation Conformational switch model Gene expression feedback control Gene Expression Regulation, Fungal Homeostasis Models, Biological Models, Theoretical Mutant Proteins - physiology Plasma Membrane Calcium-Transporting ATPases Response curve Resting level Saccharomyces cerevisiae Saccharomyces cerevisiae - physiology Saccharomyces cerevisiae Proteins - genetics Saccharomyces cerevisiae Proteins - physiology
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