Functional Specificity of the Xenopus T-Domain Protein Brachyury Is Conferred by Its Ability to Interact with Smad1

Members of the T-box gene family play important and diverse roles in development and disease. Here, we study the functional specificities of the Xenopus T-domain proteins Xbra and VegT, which differ in their abilities to induce gene expression in prospective ectodermal tissue. In particular, VegT in...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Developmental cell 2005-04, Vol.8 (4), p.599-610
Hauptverfasser:	Messenger, Nigel J., Kabitschke, Christin, Andrews, Robert, Grimmer, Donna, Miguel, Ricardo Núñez, Blundell, Tom L., Smith, James C., Wardle, Fiona C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Sequence Animals Biological and medical sciences Bone Morphogenetic Proteins - metabolism Cell differentiation, maturation, development, hematopoiesis Cell physiology DNA-Binding Proteins - chemistry DNA-Binding Proteins - genetics DNA-Binding Proteins - metabolism Ectoderm - cytology Ectoderm - physiology Fundamental and applied biological sciences. Psychology Gene Expression Regulation, Developmental Goosecoid Protein Homeodomain Proteins - genetics Homeodomain Proteins - metabolism Humans Models, Molecular Molecular and cellular biology Molecular Sequence Data Morphogenesis Protein Conformation Protein Structure, Tertiary Repressor Proteins - genetics Repressor Proteins - metabolism Sequence Alignment Signal Transduction - physiology Smad Proteins Smad1 Protein T-Box Domain Proteins - chemistry T-Box Domain Proteins - genetics T-Box Domain Proteins - metabolism Trans-Activators - chemistry Trans-Activators - genetics Trans-Activators - metabolism Transcription Factors - genetics Transcription Factors - metabolism Two-Hybrid System Techniques Xenopus laevis - embryology Xenopus laevis - physiology Xenopus Proteins - genetics Xenopus Proteins - metabolism
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!