Mutation at the Lmx1a locus provokes aberrant brain development in the rat

A rat short-tail mutation with neurological defects (named queue courte, qc) was discovered. Histopathology in adult qc/ qc rats revealed hypoplasia of the cerebellum and hippocampus, maldevelopment of the choroid plexus and corpus callosum. These abnormalities are strongly reminiscent of the phenot...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Brain research. Developmental brain research 2005-03, Vol.155 (2), p.99-106
Hauptverfasser:	Kuwamura, Mitsuru, Muraguchi, Takehiko, Matsui, Tamiko, Ueno, Mayumi, Takenaka, Shigeo, Yamate, Jyoji, Kotani, Takao, Kuramoto, Takashi, Guénet, Jean-Louis, Kitada, Kazuhiro, Serikawa, Tadao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Blotting, Northern Brain - cytology Brain - growth & development Bromodeoxyuridine Cell Movement Chromosome Mapping Cloning, Molecular Dreher Genetic Linkage - genetics Genetic Markers Homeodomain Proteins - genetics Immunohistochemistry Lmx1a Mutation - genetics Neural migration Neuroepithelial rosette Neurons - physiology Phenotype Rats RNA - genetics RNA - isolation & purification Ventricular system
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!