Critical Elements of Oligosaccharide Acceptor Substrates for the Pasteurella multocida Hyaluronan Synthase

Three-dimensional structures are not available for polysaccharide synthases and only minimal information on the molecular basis for catalysis is known. The Pasteurella multocida hyaluronan synthase (PmHAS) catalyzes the polymerization of the alternating β1,3-N-acetylglucosamine-β1,4-glucuronic acid...

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Veröffentlicht in:	The Journal of biological chemistry 2006-03, Vol.281 (9), p.5391-5397
Hauptverfasser:	Williams, Kellie J., Halkes, Koen M., Kamerling, Johannis P., DeAngelis, Paul L.
Format:	Artikel
Sprache:	eng
Schlagworte:	Carbohydrate Conformation Carbohydrate Sequence Catalytic Domain Escherichia Glucuronosyltransferase - metabolism Glycosaminoglycans - chemistry Glycosaminoglycans - metabolism Hyaluronan Synthases Molecular Sequence Data Molecular Structure Oligosaccharides - chemistry Oligosaccharides - metabolism Pasteurella multocida Pasteurella multocida - enzymology
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