Fasting triglyceride is a significant risk factor for coronary artery disease in middle-aged Japanese men
It has been well established that dyslipidemia is a significant risk factor for coronary artery disease (CAD), however, the association between fasting triglyceride (TG) and the occurrence of CAD is controversial. The objective of this study was to elucidate the relationship between fasting TG and C...
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| Veröffentlicht in: | Circulation journal : official journal of the Japanese Circulation Society 2006-03, Vol.70 (3), p.227-231 |
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| container_title | Circulation journal : official journal of the Japanese Circulation Society |
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| creator | Satoh, Hiroki Nishino, Tetsuo Tomita, Kazuo Tsutsui, Hiroyuki |
| description | It has been well established that dyslipidemia is a significant risk factor for coronary artery disease (CAD), however, the association between fasting triglyceride (TG) and the occurrence of CAD is controversial. The objective of this study was to elucidate the relationship between fasting TG and CAD in middle-aged Japanese men.
A cohort study of 6,966 middle-aged Japanese men (mean +/- SD: 46.6+/-5.2 years) with a 10-year follow-up period was conducted to identify risk factors for the occurrence of CAD. One hundred and eleven cases of CAD were identified during the follow up. The Cox proportional hazard model was used to identify the independent risk factors for CAD. Adjustment was made for variables including age, body mass index, smoking habit, alcohol intake, duration of sleeping, systolic blood pressure, uric acid, total cholesterol, high-density lipoprotein cholesterol, fasting plasma glucose, and TG. Fasting TG was identified as an independent risk factor for CAD. The adjusted hazard ratio of TG for CAD was 3.07 (95% confidence interval: 1.01-9.35, p |
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A cohort study of 6,966 middle-aged Japanese men (mean +/- SD: 46.6+/-5.2 years) with a 10-year follow-up period was conducted to identify risk factors for the occurrence of CAD. One hundred and eleven cases of CAD were identified during the follow up. The Cox proportional hazard model was used to identify the independent risk factors for CAD. Adjustment was made for variables including age, body mass index, smoking habit, alcohol intake, duration of sleeping, systolic blood pressure, uric acid, total cholesterol, high-density lipoprotein cholesterol, fasting plasma glucose, and TG. Fasting TG was identified as an independent risk factor for CAD. The adjusted hazard ratio of TG for CAD was 3.07 (95% confidence interval: 1.01-9.35, p<0.05). Additionally, a serum TG concentration level greater than 78 mg/dl was a significant risk for CAD.
By using the long term follow-up data of the study of middle-aged Japanese men, fasting TG was identified to be a significant risk factor for CAD.</description><identifier>ISSN: 1346-9843</identifier><identifier>PMID: 16501284</identifier><language>eng</language><publisher>Japan</publisher><subject>Adult ; Age Factors ; Cholesterol - blood ; Cholesterol, HDL - blood ; Cohort Studies ; Coronary Artery Disease - blood ; Coronary Artery Disease - ethnology ; Dyslipidemias - blood ; Dyslipidemias - complications ; Fasting - blood ; Humans ; Japan ; Longitudinal Studies ; Male ; Middle Aged ; Proportional Hazards Models ; Risk Factors ; Triglycerides - blood</subject><ispartof>Circulation journal : official journal of the Japanese Circulation Society, 2006-03, Vol.70 (3), p.227-231</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/16501284$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Satoh, Hiroki</creatorcontrib><creatorcontrib>Nishino, Tetsuo</creatorcontrib><creatorcontrib>Tomita, Kazuo</creatorcontrib><creatorcontrib>Tsutsui, Hiroyuki</creatorcontrib><title>Fasting triglyceride is a significant risk factor for coronary artery disease in middle-aged Japanese men</title><title>Circulation journal : official journal of the Japanese Circulation Society</title><addtitle>Circ J</addtitle><description>It has been well established that dyslipidemia is a significant risk factor for coronary artery disease (CAD), however, the association between fasting triglyceride (TG) and the occurrence of CAD is controversial. The objective of this study was to elucidate the relationship between fasting TG and CAD in middle-aged Japanese men.
A cohort study of 6,966 middle-aged Japanese men (mean +/- SD: 46.6+/-5.2 years) with a 10-year follow-up period was conducted to identify risk factors for the occurrence of CAD. One hundred and eleven cases of CAD were identified during the follow up. The Cox proportional hazard model was used to identify the independent risk factors for CAD. Adjustment was made for variables including age, body mass index, smoking habit, alcohol intake, duration of sleeping, systolic blood pressure, uric acid, total cholesterol, high-density lipoprotein cholesterol, fasting plasma glucose, and TG. Fasting TG was identified as an independent risk factor for CAD. The adjusted hazard ratio of TG for CAD was 3.07 (95% confidence interval: 1.01-9.35, p<0.05). Additionally, a serum TG concentration level greater than 78 mg/dl was a significant risk for CAD.
By using the long term follow-up data of the study of middle-aged Japanese men, fasting TG was identified to be a significant risk factor for CAD.</description><subject>Adult</subject><subject>Age Factors</subject><subject>Cholesterol - blood</subject><subject>Cholesterol, HDL - blood</subject><subject>Cohort Studies</subject><subject>Coronary Artery Disease - blood</subject><subject>Coronary Artery Disease - ethnology</subject><subject>Dyslipidemias - blood</subject><subject>Dyslipidemias - complications</subject><subject>Fasting - blood</subject><subject>Humans</subject><subject>Japan</subject><subject>Longitudinal Studies</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Proportional Hazards Models</subject><subject>Risk Factors</subject><subject>Triglycerides - blood</subject><issn>1346-9843</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2006</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNo1kDFPwzAQhT2AaCn8BeSJLZITO048oooCVSWW7tHFvkQHiRPsZOi_xxJlOD3p9L7TvXfDtrlUOjO1kht2H-OXEIURpbljm1yXIi9qtWV0gLiQ7_kSqB8uFgM55BQ58Ei9p44s-IUHit-8A7tMgXdp7BQmD-HCISyYxFFEiAn0fCTnBsygR8ePMIPHtB_RP7DbDoaIj1fdsfPh9bx_z06fbx_7l1M2l0pl2lagjCqUdTUC6rxuUQhQunK2FFVZo8QahMNCV8Z0FmRbQpcg47RrVS537Pnv7BymnxXj0owULQ5DemRaY6MrbfJKFsn4dDWu7YiumQONKVHz3438BVAvYSs</recordid><startdate>200603</startdate><enddate>200603</enddate><creator>Satoh, Hiroki</creator><creator>Nishino, Tetsuo</creator><creator>Tomita, Kazuo</creator><creator>Tsutsui, Hiroyuki</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>200603</creationdate><title>Fasting triglyceride is a significant risk factor for coronary artery disease in middle-aged Japanese men</title><author>Satoh, Hiroki ; Nishino, Tetsuo ; Tomita, Kazuo ; Tsutsui, Hiroyuki</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p544-6c7a49424cd8eae618be00a467dc50758e3e8a0de26799fca3b5afc7a9d6db413</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2006</creationdate><topic>Adult</topic><topic>Age Factors</topic><topic>Cholesterol - blood</topic><topic>Cholesterol, HDL - blood</topic><topic>Cohort Studies</topic><topic>Coronary Artery Disease - blood</topic><topic>Coronary Artery Disease - ethnology</topic><topic>Dyslipidemias - blood</topic><topic>Dyslipidemias - complications</topic><topic>Fasting - blood</topic><topic>Humans</topic><topic>Japan</topic><topic>Longitudinal Studies</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Proportional Hazards Models</topic><topic>Risk Factors</topic><topic>Triglycerides - blood</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Satoh, Hiroki</creatorcontrib><creatorcontrib>Nishino, Tetsuo</creatorcontrib><creatorcontrib>Tomita, Kazuo</creatorcontrib><creatorcontrib>Tsutsui, Hiroyuki</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Circulation journal : official journal of the Japanese Circulation Society</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Satoh, Hiroki</au><au>Nishino, Tetsuo</au><au>Tomita, Kazuo</au><au>Tsutsui, Hiroyuki</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Fasting triglyceride is a significant risk factor for coronary artery disease in middle-aged Japanese men</atitle><jtitle>Circulation journal : official journal of the Japanese Circulation Society</jtitle><addtitle>Circ J</addtitle><date>2006-03</date><risdate>2006</risdate><volume>70</volume><issue>3</issue><spage>227</spage><epage>231</epage><pages>227-231</pages><issn>1346-9843</issn><abstract>It has been well established that dyslipidemia is a significant risk factor for coronary artery disease (CAD), however, the association between fasting triglyceride (TG) and the occurrence of CAD is controversial. The objective of this study was to elucidate the relationship between fasting TG and CAD in middle-aged Japanese men.
A cohort study of 6,966 middle-aged Japanese men (mean +/- SD: 46.6+/-5.2 years) with a 10-year follow-up period was conducted to identify risk factors for the occurrence of CAD. One hundred and eleven cases of CAD were identified during the follow up. The Cox proportional hazard model was used to identify the independent risk factors for CAD. Adjustment was made for variables including age, body mass index, smoking habit, alcohol intake, duration of sleeping, systolic blood pressure, uric acid, total cholesterol, high-density lipoprotein cholesterol, fasting plasma glucose, and TG. Fasting TG was identified as an independent risk factor for CAD. The adjusted hazard ratio of TG for CAD was 3.07 (95% confidence interval: 1.01-9.35, p<0.05). Additionally, a serum TG concentration level greater than 78 mg/dl was a significant risk for CAD.
By using the long term follow-up data of the study of middle-aged Japanese men, fasting TG was identified to be a significant risk factor for CAD.</abstract><cop>Japan</cop><pmid>16501284</pmid><tpages>5</tpages></addata></record> |
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| identifier | ISSN: 1346-9843 |
| ispartof | Circulation journal : official journal of the Japanese Circulation Society, 2006-03, Vol.70 (3), p.227-231 |
| issn | 1346-9843 |
| language | eng |
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| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; J-STAGE (Japan Science & Technology Information Aggregator, Electronic) Freely Available Titles - Japanese |
| subjects | Adult Age Factors Cholesterol - blood Cholesterol, HDL - blood Cohort Studies Coronary Artery Disease - blood Coronary Artery Disease - ethnology Dyslipidemias - blood Dyslipidemias - complications Fasting - blood Humans Japan Longitudinal Studies Male Middle Aged Proportional Hazards Models Risk Factors Triglycerides - blood |
| title | Fasting triglyceride is a significant risk factor for coronary artery disease in middle-aged Japanese men |
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