Impaired Endothelium-Dependent Vasodilation in Normotensive and Normoglycemic Obese Adult Humans

Acetylcholine (ACh)-mediated endothelium-dependent vasodilation has been shown to be impaired in obese adults. However, the mechanisms responsible for this impairment are not clear. We determined whether the blunted forearm vasodilator response to acetylcholine with obesity is due, at least in part,...

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Veröffentlicht in:	Journal of cardiovascular pharmacology 2006-02, Vol.47 (2), p.310-313
Hauptverfasser:	Van Guilder, Gary P, Hoetzer, Greta L, Dengel, Donald R, Stauffer, Brian L, DeSouza, Christopher A
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetylcholine - pharmacology Blood Glucose - metabolism Blood Pressure - physiology Case-Control Studies Dose-Response Relationship, Drug Endothelium, Vascular - drug effects Endothelium, Vascular - physiopathology Female Humans Male Middle Aged Nitroprusside - pharmacology Obesity - physiopathology Vasodilation - physiology Vasodilator Agents - pharmacology
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