Transcription factor YY1: structure, function, and therapeutic implications in cancer biology

The ubiquitous transcription factor Yin Yang 1 (YY1) is known to have a fundamental role in normal biologic processes such as embryogenesis, differentiation, replication, and cellular proliferation. YY1 exerts its effects on genes involved in these processes via its ability to initiate, activate, or...

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Veröffentlicht in:	Oncogene 2006-02, Vol.25 (8), p.1125-1142
Hauptverfasser:	Gordon, S, Akopyan, G, Garban, H, Bonavida, B
Format:	Artikel
Sprache:	eng
Schlagworte:	Ageing, cell death Animals Antitumor activity Apoptosis Base Sequence Binding sites Biological and medical sciences Biology c-Myc protein Cancer Cell Biology Cell cycle Cell physiology Cell transformation and carcinogenesis. Action of oncogenes and antioncogenes Chemotherapy Cloning DNA binding proteins Embryogenesis Fundamental and applied biological sciences. Psychology Gene expression Gene regulation Genes Health aspects Hepatocellular carcinoma Human Genetics Humans Hypotheses Immunology Immunotherapy Inflammation Internal Medicine Medical Oncology Medicine Medicine & Public Health Metastases Molecular and cellular biology Molecular genetics Molecular modelling Molecular Sequence Data Myc protein Neoplasms - diagnosis Neoplasms - metabolism Neoplasms - therapy NF-κB protein Oncology p53 Protein Proteins Retina Retinoblastoma review Ribose Structure-function relationships Transcription factors Transcription. Transcription factor. Splicing. Rna processing Transplants & implants Tumor markers Tumor proteins Tumorigenesis Tumors YY1 protein YY1 Transcription Factor - chemistry YY1 Transcription Factor - metabolism YY1 Transcription Factor - therapeutic use
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