T-cell responses during pig-to-primate xenotransplantation

: Xenotransplantation using porcine organs may resolve a chronic shortage of donor organs for clinical transplantation if significant immunological barriers can be overcome. To determine the potential role of T lymphocytes in Xenograft (Xg) rejection, we transplanted transgenic hCD46 porcine hearts...

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Veröffentlicht in:	Xenotransplantation (Københaven) 2006-01, Vol.13 (1), p.31-40
Hauptverfasser:	Davila, Eduardo, Byrne, Guerard W., LaBreche, Peter T., McGregor, Hugh C. J., Schwab, Allison K., Davies, William R., Rao, Vinay P., Oi, Keiji, Tazelaar, Henry D., Logan, John S., McGregor, Christopher G. A.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Animals, Genetically Modified Antibodies, Monoclonal - immunology Antibodies, Monoclonal, Murine-Derived Antigens - immunology cell activation Cells, Cultured cytotoxicity Endothelial Cells - cytology Endothelial Cells - immunology Graft Rejection - immunology Heart Transplantation - immunology Humans Lymphocyte Activation Papio Rituximab Swine T cells T-Lymphocytes - immunology transplantation Transplantation, Heterologous - immunology
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