Pervasive transcription of the eukaryotic genome: functional indices and conceptual implications

Genome-wide analyses of the eukaryotic transcriptome have revealed that the majority of the genome is transcribed, producing large numbers of non-protein-coding RNAs (ncRNAs). This surprising observation challenges many assumptions about the genetic programming of higher organisms and how informatio...

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Veröffentlicht in:	Briefings in functional genomics & proteomics 2009-11, Vol.8 (6), p.407-423
Hauptverfasser:	Dinger, Marcel E., Amaral, Paulo P., Mercer, Timothy R., Mattick, John S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Eukaryotes Eukaryotic Cells - metabolism Gene Expression Profiling Genome Genomics Humans Proteins Proteomics Ribonucleic acid RNA RNA, Messenger - genetics RNA, Untranslated - genetics Transcription, Genetic
Online-Zugang:	Volltext
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